Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   CH624_RS03010 Genome accession   NZ_CP031682
Coordinates   593010..594347 (+) Length   445 a.a.
NCBI ID   WP_005659796.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P665-7858     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 588010..599347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH624_RS02985 (CH624_02985) - 588075..590669 (-) 2595 WP_112109799.1 penicillin-binding protein 1A -
  CH624_RS02990 (CH624_02990) comA 590768..591565 (+) 798 WP_005652119.1 pilus assembly protein PilM Machinery gene
  CH624_RS02995 (CH624_02995) comB 591566..592072 (+) 507 WP_042611002.1 competence protein ComB Machinery gene
  CH624_RS03000 (CH624_03000) comC 592069..592590 (+) 522 WP_112109798.1 competence protein ComC Machinery gene
  CH624_RS03005 (CH624_03005) comD 592587..593000 (+) 414 WP_112109797.1 competence protein Machinery gene
  CH624_RS03010 (CH624_03010) comE 593010..594347 (+) 1338 WP_005659796.1 type IV pilus secretin PilQ family protein Machinery gene
  CH624_RS03015 (CH624_03015) - 594360..595046 (+) 687 WP_116937985.1 ComF family protein -
  CH624_RS03020 (CH624_03020) nfuA 595122..595718 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  CH624_RS03025 (CH624_03025) nudC 595785..596579 (+) 795 WP_116937984.1 NAD(+) diphosphatase -
  CH624_RS03030 (CH624_03030) - 596615..597205 (+) 591 WP_005691398.1 YjaG family protein -
  CH624_RS03035 (CH624_03035) - 597346..597618 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49108.40 Da        Isoelectric Point: 7.4794

>NTDB_id=309918 CH624_RS03010 WP_005659796.1 593010..594347(+) (comE) [Haemophilus influenzae strain P665-7858]
MKKYFLKCGCFLVFFCLPLIVFANPKTDNERFFIRLSQAPLAQTVEQLAFQQDVNLVIGDILESKISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGIYYLNGSQSGKGEVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=309918 CH624_RS03010 WP_005659796.1 593010..594347(+) (comE) [Haemophilus influenzae strain P665-7858]
ATGAAGAAATATTTTTTAAAGTGCGGTTGTTTTTTAGTATTTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACAGTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATTGGAGATATATTGGAAAGCAAGATCTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGATTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TGAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCTTTAACAACAGGAAGTGGCTCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTCGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

97.978

100

0.98
  comE Haemophilus influenzae 86-028NP

96.629

100

0.966
  comE Glaesserella parasuis strain SC1401

52.204

96.854

0.506
  pilQ Vibrio campbellii strain DS40M4

41.844

95.056

0.398
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.505

92.584

0.384
  pilQ Vibrio cholerae strain A1552

41.505

92.584

0.384

Multiple sequence alignment