Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   CH631_RS03000 Genome accession   NZ_CP031680
Coordinates   600341..601678 (+) Length   445 a.a.
NCBI ID   WP_116939826.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P672-7661     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 595341..606678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH631_RS02975 (CH631_02975) - 595406..598000 (-) 2595 WP_116939818.1 penicillin-binding protein 1A -
  CH631_RS02980 (CH631_02980) comA 598099..598896 (+) 798 WP_116939820.1 competence protein ComA Machinery gene
  CH631_RS02985 (CH631_02985) comB 598897..599403 (+) 507 WP_116939822.1 competence protein ComB Machinery gene
  CH631_RS02990 (CH631_02990) comC 599400..599921 (+) 522 WP_112084028.1 competence protein ComC Machinery gene
  CH631_RS02995 (CH631_02995) comD 599918..600331 (+) 414 WP_116939824.1 pilus assembly protein PilP Machinery gene
  CH631_RS03000 (CH631_03000) comE 600341..601678 (+) 1338 WP_116939826.1 type IV pilus secretin PilQ family protein Machinery gene
  CH631_RS03005 (CH631_03005) - 601691..602377 (+) 687 WP_012055030.1 ComF family protein -
  CH631_RS03010 (CH631_03010) nfuA 602453..603049 (+) 597 WP_116939827.1 Fe-S biogenesis protein NfuA -
  CH631_RS03015 (CH631_03015) nudC 603116..603910 (+) 795 WP_116939829.1 NAD(+) diphosphatase -
  CH631_RS03020 (CH631_03020) - 603946..604536 (+) 591 WP_116939830.1 YjaG family protein -
  CH631_RS03025 (CH631_03025) - 604677..604949 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49126.40 Da        Isoelectric Point: 8.2628

>NTDB_id=309848 CH631_RS03000 WP_116939826.1 600341..601678(+) (comE) [Haemophilus influenzae strain P672-7661]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLAALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=309848 CH631_RS03000 WP_116939826.1 600341..601678(+) (comE) [Haemophilus influenzae strain P672-7661]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCTTTAACAACAGGAAGTGGCTCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTAATTGCTGAAATGGATAAGCCTATTGAGCA
GATCGCTATTGAAGCACGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCGCATAT
TTTAAAAGCGGGGGAAACGTTAGCGGCGTTGAAACAAAAAAGTGCGGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.876

100

0.989
  comE Haemophilus influenzae Rd KW20

97.753

100

0.978
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.584

0.391
  pilQ Vibrio cholerae strain A1552

42.233

92.584

0.391

Multiple sequence alignment