Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   DY470_RS14210 Genome accession   NZ_CP031642
Coordinates   2677650..2678231 (-) Length   193 a.a.
NCBI ID   WP_000991628.1    Uniprot ID   A0A243D1Q7
Organism   Bacillus anthracis strain MCCC 1A02161     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2672650..2683231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DY470_RS14180 (DY470_14180) - 2672662..2673498 (-) 837 WP_071735920.1 PP2C family serine/threonine-protein phosphatase -
  DY470_RS14185 (DY470_14185) - 2673482..2673973 (-) 492 WP_002021523.1 HIT family protein -
  DY470_RS14190 (DY470_14190) - 2674076..2674243 (-) 168 WP_002053336.1 hypothetical protein -
  DY470_RS14195 (DY470_14195) - 2674541..2675377 (-) 837 WP_001084757.1 proline/glycine betaine ABC transporter permease -
  DY470_RS14200 (DY470_14200) - 2675370..2676575 (-) 1206 WP_000370609.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  DY470_RS14205 (DY470_14205) - 2676747..2677604 (+) 858 WP_001227634.1 glycine betaine ABC transporter substrate-binding protein -
  DY470_RS14210 (DY470_14210) clpP 2677650..2678231 (-) 582 WP_000991628.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  DY470_RS14215 (DY470_14215) - 2678253..2678939 (-) 687 WP_071735921.1 RNA polymerase subunit sigma-70 -
  DY470_RS14220 (DY470_14220) - 2679082..2679402 (+) 321 WP_001125378.1 2Fe-2S iron-sulfur cluster-binding protein -
  DY470_RS14225 (DY470_14225) rpiA 2679407..2680069 (+) 663 WP_071735922.1 ribose 5-phosphate isomerase A -
  DY470_RS14230 (DY470_14230) - 2680177..2680611 (+) 435 WP_071735923.1 GNAT family N-acetyltransferase -
  DY470_RS14235 (DY470_14235) - 2680742..2682109 (-) 1368 WP_071735924.1 lytic polysaccharide monooxygenase -
  DY470_RS14240 (DY470_14240) - 2682546..2683064 (-) 519 WP_000720566.1 DNA topology modulation protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21208.45 Da        Isoelectric Point: 5.0776

>NTDB_id=309291 DY470_RS14210 WP_000991628.1 2677650..2678231(-) (clpP) [Bacillus anthracis strain MCCC 1A02161]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGTKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=309291 DY470_RS14210 WP_000991628.1 2677650..2678231(-) (clpP) [Bacillus anthracis strain MCCC 1A02161]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCCATATTAGATACG
ATGAATTTAATCAAACCAGACGTACAAACGCTATGCATGGGATTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TACAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCACAAGGGCAAGCGA
CGGAAATCGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATCGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A243D1Q7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

66.138

97.927

0.648
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

54.167

99.482

0.539
  clpP Streptococcus pneumoniae D39

54.167

99.482

0.539
  clpP Streptococcus pneumoniae R6

54.167

99.482

0.539
  clpP Streptococcus pneumoniae TIGR4

54.167

99.482

0.539
  clpP Streptococcus mutans UA159

52.91

97.927

0.518
  clpP Lactococcus lactis subsp. cremoris KW2

52.381

97.927

0.513
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492

Multiple sequence alignment