Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DZN22_RS08460 Genome accession   NZ_CP031637
Coordinates   1644004..1644555 (-) Length   183 a.a.
NCBI ID   WP_076638078.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS10786     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1639004..1649555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DZN22_RS08425 (DZN22_08415) - 1639007..1639750 (-) 744 WP_021340917.1 class I SAM-dependent methyltransferase -
  DZN22_RS08430 (DZN22_08420) rsfS 1639798..1640151 (-) 354 WP_032459751.1 ribosome silencing factor -
  DZN22_RS08435 (DZN22_08425) yqeK 1640175..1640768 (-) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DZN22_RS08440 (DZN22_08430) - 1640765..1641397 (-) 633 WP_002991091.1 nicotinate-nucleotide adenylyltransferase -
  DZN22_RS08445 (DZN22_08435) yhbY 1641466..1641774 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  DZN22_RS08450 (DZN22_08440) yqeH 1641800..1642918 (-) 1119 WP_002985994.1 ribosome biogenesis GTPase YqeH -
  DZN22_RS08455 (DZN22_08445) - 1642918..1643445 (-) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DZN22_RS08460 (DZN22_08450) comX/sigX/comX2/sigX2 1644004..1644555 (-) 552 WP_076638078.1 competence protein ComX Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22228.03 Da        Isoelectric Point: 9.8369

>NTDB_id=309074 DZN22_RS08460 WP_076638078.1 1644004..1644555(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain MGAS10786]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLCRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=309074 DZN22_RS08460 WP_076638078.1 1644004..1644555(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain MGAS10786]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTATGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

43.791

83.607

0.366

Multiple sequence alignment