Detailed information NTG0000309

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: STER_RS08975
• Genome accession: NC_008532
• Coordinates: 1709364..1709801 (-)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus LMD-9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1704364..1714801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STER_RS08935 (STER_1829)	-	1704428..1705090 (-)	663	WP_011681679.1	CPBP family intramembrane glutamic endopeptidase	-
STER_RS08940 (STER_1830)	-	1705187..1705630 (-)	444	WP_011681680.1	hypothetical protein	-
STER_RS11960 (STER_1831)	-	1705704..1706042 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
STER_RS11965 (STER_1832)	-	1706086..1706361 (-)	276	WP_011681681.1	hypothetical protein	-
STER_RS08955 (STER_1833)	-	1706373..1706570 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STER_RS08960 (STER_1834)	-	1706819..1708012 (-)	1194	WP_011681683.1	acetate kinase	-
STER_RS08965 (STER_1835)	comYH	1708068..1709024 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
STER_RS08970 (STER_1836)	comGG	1709069..1709386 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	Machinery gene
STER_RS08975 (STER_1837)	comGF	1709364..1709801 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
STER_RS08980 (STER_1838)	comGE	1709785..1710078 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
STER_RS08985 (STER_1839)	comGD	1710050..1710478 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STER_RS08990 (STER_1840)	comGC	1710438..1710764 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STER_RS08995 (STER_1841)	comGB	1710761..1711861 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STER_RS09000 (STER_1842)	comGA	1711743..1712684 (-)	942	WP_011681689.1	competence type IV pilus ATPase ComGA	Machinery gene
STER_RS09005 (STER_1843)	-	1712765..1713127 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=309 STER_RS08975 WP_011681686.1 1709364..1709801(-) (comGF) [Streptococcus thermophilus LMD-9]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=309 STER_RS08975 WP_011681686.1 1709364..1709801(-) (comGF) [Streptococcus thermophilus LMD-9]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434