Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DV130_RS12860 Genome accession   NZ_CP031248
Coordinates   982924..983823 (+) Length   299 a.a.
NCBI ID   WP_050072943.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 977924..988823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS05115 - 978191..978976 (-) 786 Protein_994 IS5 family transposase -
  DV130_RS05120 - 979179..979583 (-) 405 WP_000846943.1 hypothetical protein -
  DV130_RS12180 - 979580..979744 (-) 165 WP_000727118.1 hypothetical protein -
  DV130_RS05130 - 980041..980160 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  DV130_RS05135 blpU 980163..980393 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  DV130_RS05140 blpJ 980462..980731 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  DV130_RS05150 blpI 981198..981395 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  DV130_RS12850 comA/nlmT 981677..982264 (+) 588 WP_050088117.1 cysteine peptidase family C39 domain-containing protein Regulator
  DV130_RS12855 comA/nlmT 982209..982934 (+) 726 WP_306341168.1 ABC transporter transmembrane domain-containing protein Regulator
  DV130_RS12860 comA/nlmT 982924..983823 (+) 900 WP_050072943.1 ATP-binding cassette domain-containing protein Regulator
  DV130_RS05165 - 983834..985156 (+) 1323 WP_306341167.1 bacteriocin secretion accessory protein -
  DV130_RS05170 - 985222..986568 (+) 1347 WP_050072287.1 IS1380-like element ISSpn5 family transposase -
  DV130_RS05175 - 986762..986902 (+) 141 Protein_1006 bacteriocin ABC transporter ATP-binding protein -
  DV130_RS05180 blpC 986959..987114 (+) 156 WP_061450964.1 quorum-sensing system pheromone BlpC -
  DV130_RS05185 - 987158..988498 (-) 1341 WP_050073044.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 33536.45 Da        Isoelectric Point: 6.8361

>NTDB_id=304895 DV130_RS12860 WP_050072943.1 982924..983823(+) (comA/nlmT) [Streptococcus pneumoniae strain M26365]
MSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYG
FGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSI
LENLTLGGNHMISQEDILKACEVAEIRQDIEGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKK
VIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=304895 DV130_RS12860 WP_050072943.1 982924..983823(+) (comA/nlmT) [Streptococcus pneumoniae strain M26365]
ATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATAT
TATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAAT
TTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGT
TTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTC
TGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATA
TTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATT
TTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCG
TCAAGACATTGAAGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCG
CTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAG
GTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAA
CCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACC
ATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(86-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.192

100

0.719
  comA Streptococcus mitis NCTC 12261

65.347

100

0.662
  comA Streptococcus gordonii str. Challis substr. CH1

64.59

100

0.659
  comA Streptococcus pneumoniae D39

64.686

100

0.656
  comA Streptococcus pneumoniae R6

64.686

100

0.656
  comA Streptococcus pneumoniae Rx1

64.686

100

0.656
  comA Streptococcus mitis SK321

64.356

100

0.652
  comA Streptococcus pneumoniae TIGR4

64.356

100

0.652

Multiple sequence alignment