Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DV129_RS09150 Genome accession   NZ_CP031247
Coordinates   1690411..1690713 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1685411..1695713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS09120 - 1686168..1687226 (+) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  DV129_RS09125 - 1687377..1687742 (+) 366 WP_000286415.1 DUF1033 family protein -
  DV129_RS09130 comGA/cglA/cilD 1687818..1688759 (+) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  DV129_RS09135 comGB/cglB 1688707..1689723 (+) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV129_RS09140 comGC/cglC 1689725..1690051 (+) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  DV129_RS09145 comGD/cglD 1690044..1690448 (+) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV129_RS09150 comGE/cglE 1690411..1690713 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV129_RS09155 comGF/cglF 1690676..1691137 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV129_RS09160 comGG/cglG 1691115..1691528 (+) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV129_RS09170 - 1691665..1692259 (+) 595 Protein_1712 methyltransferase domain-containing protein -
  DV129_RS09175 comYH 1692320..1693273 (+) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  DV129_RS09180 - 1693324..1694514 (+) 1191 WP_000167766.1 acetate kinase -
  DV129_RS12550 - 1694515..1694646 (+) 132 WP_000768904.1 hypothetical protein -
  DV129_RS09185 rnpA 1694663..1695034 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=304793 DV129_RS09150 WP_000413382.1 1690411..1690713(+) (comGE/cglE) [Streptococcus pneumoniae strain M23734]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=304793 DV129_RS09150 WP_000413382.1 1690411..1690713(+) (comGE/cglE) [Streptococcus pneumoniae strain M23734]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment