Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   DV129_RS09140 Genome accession   NZ_CP031247
Coordinates   1689725..1690051 (+) Length   108 a.a.
NCBI ID   WP_000738633.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1684725..1695051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS09115 nagA 1684854..1686005 (+) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  DV129_RS09120 - 1686168..1687226 (+) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  DV129_RS09125 - 1687377..1687742 (+) 366 WP_000286415.1 DUF1033 family protein -
  DV129_RS09130 comGA/cglA/cilD 1687818..1688759 (+) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  DV129_RS09135 comGB/cglB 1688707..1689723 (+) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV129_RS09140 comGC/cglC 1689725..1690051 (+) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  DV129_RS09145 comGD/cglD 1690044..1690448 (+) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV129_RS09150 comGE/cglE 1690411..1690713 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV129_RS09155 comGF/cglF 1690676..1691137 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV129_RS09160 comGG/cglG 1691115..1691528 (+) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV129_RS09170 - 1691665..1692259 (+) 595 Protein_1712 methyltransferase domain-containing protein -
  DV129_RS09175 comYH 1692320..1693273 (+) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  DV129_RS09180 - 1693324..1694514 (+) 1191 WP_000167766.1 acetate kinase -
  DV129_RS12550 - 1694515..1694646 (+) 132 WP_000768904.1 hypothetical protein -
  DV129_RS09185 rnpA 1694663..1695034 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12222.42 Da        Isoelectric Point: 10.0305

>NTDB_id=304791 DV129_RS09140 WP_000738633.1 1689725..1690051(+) (comGC/cglC) [Streptococcus pneumoniae strain M23734]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEYNDKNVGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=304791 DV129_RS09140 WP_000738633.1 1689725..1690051(+) (comGC/cglC) [Streptococcus pneumoniae strain M23734]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAATACAATGATAAAAATGTAGGAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954

  comGC/cglC Streptococcus pneumoniae Rx1

94.444

100

0.944

  comGC/cglC Streptococcus pneumoniae D39

94.444

100

0.944

  comGC/cglC Streptococcus pneumoniae R6

94.444

100

0.944

  comGC/cglC Streptococcus mitis SK321

91.667

100

0.917

  comGC/cglC Streptococcus mitis NCTC 12261

91.919

91.667

0.843

  comYC Streptococcus gordonii str. Challis substr. CH1

70.833

88.889

0.63

  comYC Streptococcus mutans UA159

61.765

94.444

0.583

  comYC Streptococcus mutans UA140

61.765

94.444

0.583

  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528

  comYC Streptococcus suis isolate S10

66.667

75

0.5

  comGC Staphylococcus aureus MW2

48.837

79.63

0.389

  comGC Staphylococcus aureus N315

48.837

79.63

0.389

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361


Multiple sequence alignment