Detailed information NTG0302631

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DS740_RS18695
• Genome accession: NZ_CP030937
• Coordinates: 3559989..3560582 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus sp. DM2
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3554989..3565582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DS740_RS18665 (DS740_18665)	aspP	3555961..3557523 (+)	1563	WP_003228228.1	aspartate/proton symporter AspP	-
DS740_RS18670 (DS740_18670)	-	3557618..3558202 (+)	585	WP_003244443.1	TetR family transcriptional regulator	-
DS740_RS18675 (DS740_18675)	-	3558285..3558620 (+)	336	WP_041850504.1	QacE family quaternary ammonium compound efflux SMR transporter	-
DS740_RS18680 (DS740_18680)	-	3558620..3558940 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
DS740_RS18685 (DS740_18685)	-	3558976..3559488 (-)	513	WP_014478056.1	DUF3231 family protein	-
DS740_RS18695 (DS740_18695)	clpP	3559989..3560582 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
DS740_RS18700 (DS740_18700)	pgmB	3560627..3561301 (-)	675	WP_041850503.1	beta-phosphoglucomutase	-
DS740_RS18705 (DS740_18705)	malL	3561298..3562983 (-)	1686	WP_041850502.1	oligo-1,6-glucosidase	-
DS740_RS18710 (DS740_18710)	mdxK	3562976..3565249 (-)	2274	WP_041850501.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=302631 DS740_RS18695 WP_003228214.1 3559989..3560582(+) (clpP) [Bacillus sp. DM2]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=302631 DS740_RS18695 WP_003228214.1 3559989..3560582(+) (clpP) [Bacillus sp. DM2]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCACTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGTGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538