Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DP112_RS07475 Genome accession   NZ_CP030125
Coordinates   1484609..1485313 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain HA1003     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1479609..1490313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS07460 (DP112_07460) vga(F) 1480818..1482203 (-) 1386 WP_164503922.1 ABC-F type ribosomal protection protein Vga(F) -
  DP112_RS07465 (DP112_07465) vicX 1482457..1483260 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  DP112_RS07470 (DP112_07470) micB 1483267..1484616 (-) 1350 WP_114866693.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DP112_RS07475 (DP112_07475) micA 1484609..1485313 (-) 705 WP_004298854.1 response regulator YycF Regulator
  DP112_RS07480 (DP112_07480) - 1485507..1486268 (+) 762 WP_114866694.1 amino acid ABC transporter ATP-binding protein -
  DP112_RS07485 (DP112_07485) - 1486279..1487118 (+) 840 WP_114866695.1 transporter substrate-binding domain-containing protein -
  DP112_RS07490 (DP112_07490) - 1487133..1487831 (+) 699 WP_024410916.1 amino acid ABC transporter permease -
  DP112_RS07495 (DP112_07495) - 1487846..1488505 (+) 660 WP_024384909.1 amino acid ABC transporter permease -
  DP112_RS07505 (DP112_07505) - 1488657..1489520 (-) 864 WP_125330197.1 hypothetical protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=299492 DP112_RS07475 WP_004298854.1 1484609..1485313(-) (micA) [Streptococcus suis strain HA1003]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=299492 DP112_RS07475 WP_004298854.1 1484609..1485313(-) (micA) [Streptococcus suis strain HA1003]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGCGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTCTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAAACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGTACGGTGGATGTAACGATTCGTCGCCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment