Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DP112_RS07470 Genome accession   NZ_CP030125
Coordinates   1483267..1484616 (-) Length   449 a.a.
NCBI ID   WP_114866693.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1478267..1489616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS07455 (DP112_07455) pbp2b 1478651..1480726 (-) 2076 WP_114866692.1 penicillin-binding protein PBP2B -
  DP112_RS07460 (DP112_07460) vga(F) 1480818..1482203 (-) 1386 WP_164503922.1 ABC-F type ribosomal protection protein Vga(F) -
  DP112_RS07465 (DP112_07465) vicX 1482457..1483260 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  DP112_RS07470 (DP112_07470) micB 1483267..1484616 (-) 1350 WP_114866693.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DP112_RS07475 (DP112_07475) micA 1484609..1485313 (-) 705 WP_004298854.1 response regulator YycF Regulator
  DP112_RS07480 (DP112_07480) - 1485507..1486268 (+) 762 WP_114866694.1 amino acid ABC transporter ATP-binding protein -
  DP112_RS07485 (DP112_07485) - 1486279..1487118 (+) 840 WP_114866695.1 transporter substrate-binding domain-containing protein -
  DP112_RS07490 (DP112_07490) - 1487133..1487831 (+) 699 WP_024410916.1 amino acid ABC transporter permease -
  DP112_RS07495 (DP112_07495) - 1487846..1488505 (+) 660 WP_024384909.1 amino acid ABC transporter permease -
  DP112_RS07505 (DP112_07505) - 1488657..1489520 (-) 864 WP_125330197.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51067.13 Da        Isoelectric Point: 4.5202

>NTDB_id=299491 DP112_RS07470 WP_114866693.1 1483267..1484616(-) (micB) [Streptococcus suis strain HA1003]
MINQLRYLMTTVEFWFIVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLSSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=299491 DP112_RS07470 WP_114866693.1 1483267..1484616(-) (micB) [Streptococcus suis strain HA1003]
ATGATTAATCAATTACGTTATTTAATGACCACGGTAGAATTTTGGTTTATTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATTTGTCGGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGTCTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATTATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTGAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGTTCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.413

97.105

0.684
  vicK Streptococcus mutans UA159

70.471

89.755

0.633

Multiple sequence alignment