Detailed information NTG0298364

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DK875_RS03700
• Genome accession: NZ_CP030020
• Coordinates: 761062..763299 (+)
• Length: 745 a.a.
• NCBI ID: WP_002935350.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2514
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 756062..768299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK875_RS03675 (DK875_03865)	-	756132..757061 (-)	930	WP_002937175.1	ABC transporter substrate-binding protein	-
DK875_RS03680 (DK875_03870)	-	757074..757859 (-)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
DK875_RS03685 (DK875_03875)	-	758011..759456 (-)	1446	WP_024390938.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
DK875_RS03690 (DK875_03880)	-	759603..760349 (+)	747	WP_014636901.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
DK875_RS03695 (DK875_03885)	comEA/celA/cilE	760416..761078 (+)	663	WP_002935348.1	helix-hairpin-helix domain-containing protein	Machinery gene
DK875_RS03700 (DK875_03890)	comEC/celB	761062..763299 (+)	2238	WP_002935350.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DK875_RS03705 (DK875_03895)	-	763623..764279 (+)	657	WP_002935353.1	CBS domain-containing protein	-
DK875_RS03710 (DK875_03900)	-	764373..765200 (+)	828	WP_002935354.1	hypothetical protein	-
DK875_RS03715 (DK875_03905)	-	765206..766477 (+)	1272	WP_002935355.1	toxic anion resistance protein	-
DK875_RS03720 (DK875_03910)	-	766514..767380 (-)	867	WP_002935357.1	YitT family protein	-
DK875_RS03725 (DK875_03915)	tmk	767555..768193 (+)	639	WP_002935358.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84195.14 Da
• Isoelectric Point: 7.3813

>NTDB_id=298364 DK875_RS03700 WP_002935350.1 761062..763299(+) (comEC/celB) [Streptococcus suis strain ISU2514]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGCQKVQWERADQLA
PEQVTTMQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFVIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVEVGERLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=298364 DK875_RS03700 WP_002935350.1 761062..763299(+) (comEC/celB) [Streptococcus suis strain ISU2514]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTTTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTATGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGATAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGCCTGCCAGCAGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTGTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATTAATGTCCCTGTTCATGTTGTTGAGGTGGGCGAACGCTTACCAATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.836	99.732	0.537
comEC/celB	Streptococcus mitis NCTC 12261	52.632	99.463	0.523
comEC/celB	Streptococcus pneumoniae TIGR4	51.752	99.597	0.515
comEC/celB	Streptococcus pneumoniae Rx1	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae D39	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae R6	51.482	99.597	0.513
comEC	Lactococcus lactis subsp. cremoris KW2	48.594	100	0.487