Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   DK875_RS04985 Genome accession   NZ_CP030020
Coordinates   1030763..1031605 (-) Length   280 a.a.
NCBI ID   WP_002936492.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2514     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1025763..1036605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS04960 (DK875_05195) - 1025886..1026704 (-) 819 WP_024401260.1 replication initiator protein A -
  DK875_RS04965 (DK875_05200) - 1026707..1026874 (-) 168 WP_032499127.1 hypothetical protein -
  DK875_RS04970 (DK875_05205) rplL 1027075..1027440 (-) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  DK875_RS04975 (DK875_05210) rplJ 1027506..1028000 (-) 495 WP_002936486.1 50S ribosomal protein L10 -
  DK875_RS04980 (DK875_05215) topA 1028577..1030670 (-) 2094 WP_013730365.1 type I DNA topoisomerase -
  DK875_RS04985 (DK875_05220) dprA 1030763..1031605 (-) 843 WP_002936492.1 DNA-processing protein DprA Machinery gene
  DK875_RS04990 (DK875_05225) - 1031664..1032128 (-) 465 WP_002936493.1 sugar O-acetyltransferase -
  DK875_RS04995 (DK875_05230) - 1032149..1032409 (-) 261 WP_009909865.1 metal-sensitive transcriptional regulator -
  DK875_RS05000 (DK875_05235) - 1032528..1032851 (+) 324 WP_002936495.1 rhodanese-like domain-containing protein -
  DK875_RS05005 (DK875_05240) - 1032848..1034548 (+) 1701 WP_053866445.1 FAD-dependent oxidoreductase -
  DK875_RS05010 (DK875_05245) - 1034604..1035155 (+) 552 WP_002936497.1 DUF1836 domain-containing protein -
  DK875_RS05015 (DK875_05250) - 1035145..1035795 (+) 651 WP_053866444.1 hemolysin III family protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31261.11 Da        Isoelectric Point: 8.4451

>NTDB_id=298366 DK875_RS04985 WP_002936492.1 1030763..1031605(-) (dprA) [Streptococcus suis strain ISU2514]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAIVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=298366 DK875_RS04985 WP_002936492.1 1030763..1031605(-) (dprA) [Streptococcus suis strain ISU2514]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTATAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCGCCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATTGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATCGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGAAATCGCATCATTGCTGGGTTGG
TAGAAGGATTGGTAGTCTGTGAGGCTAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.286

100

0.693
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.357

100

0.604
  dprA Legionella pneumophila strain ERS1305867

41.7

88.214

0.368
  dprA Bacillus subtilis subsp. subtilis str. 168

50.746

71.786

0.364

Multiple sequence alignment