Detailed information NTG0295441

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DMC40_RS08175
• Genome accession: NZ_CP029694
• Coordinates: 1543080..1543670 (-)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain ABC020055975
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1538080..1548670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DMC40_RS08135 (DMC40_08135)	-	1538262..1538654 (-)	393	WP_002985833.1	DUF5684 domain-containing protein	-
DMC40_RS08140 (DMC40_08140)	rsmI	1538681..1539544 (-)	864	WP_011054222.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
DMC40_RS08145 (DMC40_08145)	yabA	1539549..1539872 (-)	324	WP_011054221.1	DNA replication initiation control protein YabA	-
DMC40_RS10010	-	1540371..1540517 (-)	147	WP_227868520.1	hypothetical protein	-
DMC40_RS08155 (DMC40_08155)	-	1540536..1541411 (-)	876	WP_011054220.1	DNA polymerase III subunit delta'	-
DMC40_RS08160 (DMC40_08160)	tmk	1541429..1542064 (-)	636	WP_011054219.1	dTMP kinase	-
DMC40_RS08165 (DMC40_08165)	-	1542313..1542588 (-)	276	WP_002985847.1	YlbG family protein	-
DMC40_RS08175 (DMC40_08170)	clpP	1543080..1543670 (-)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
DMC40_RS08185 (DMC40_08180)	upp	1543893..1544522 (-)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
DMC40_RS08190 (DMC40_08185)	-	1544690..1546324 (-)	1635	WP_011054218.1	polysaccharide biosynthesis protein	-
DMC40_RS08195 (DMC40_08190)	-	1546412..1547857 (+)	1446	WP_011054217.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=295441 DMC40_RS08175 WP_002985850.1 1543080..1543670(-) (clpP) [Streptococcus pyogenes strain ABC020055975]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=295441 DMC40_RS08175 WP_002985850.1 1543080..1543670(-) (clpP) [Streptococcus pyogenes strain ABC020055975]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGGAAA
ACGATTAAACAAATTCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561