Detailed information NTG0294155

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DL538_RS18525
• Genome accession: NZ_CP029609
• Coordinates: 3529975..3530568 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis subsp. subtilis strain G7
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3524975..3535568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DL538_RS18495 (DL538_18390)	psmA	3525230..3525565 (+)	336	WP_131228134.1	multidrug efflux SMR transporter	-
DL538_RS18500 (DL538_18395)	psmB	3525565..3525885 (+)	321	WP_076457550.1	multidrug efflux SMR transporter	-
DL538_RS18505 (DL538_18400)	yvdQ	3525921..3526433 (-)	513	WP_106073377.1	DUF3231 family protein	-
DL538_RS18510 (DL538_18405)	cotNP	3526685..3528028 (-)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
DL538_RS18515 (DL538_18410)	cotR	3528384..3529346 (+)	963	WP_003243674.1	sporulation hydrolase CotR	-
DL538_RS18525 (DL538_18420)	clpP	3529975..3530568 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
DL538_RS18530 (DL538_18425)	pgmB	3530612..3531286 (-)	675	WP_131228135.1	beta-phosphoglucomutase	-
DL538_RS18535 (DL538_18430)	malL	3531283..3532968 (-)	1686	WP_131228136.1	oligo-1,6-glucosidase	-
DL538_RS18540 (DL538_18435)	mdxK	3532961..3535234 (-)	2274	WP_131228137.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=294155 DL538_RS18525 WP_003228214.1 3529975..3530568(+) (clpP) [Bacillus subtilis subsp. subtilis strain G7]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=294155 DL538_RS18525 WP_003228214.1 3529975..3530568(+) (clpP) [Bacillus subtilis subsp. subtilis strain G7]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGTGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538