Detailed information NTG0293217

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DK182_RS06120
• Genome accession: NZ_CP029491
• Coordinates: 1219243..1220082 (-)
• Length: 279 a.a.
• NCBI ID: WP_002962319.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain 10919
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1214243..1225082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK182_RS06105 (DK181_06105)	-	1214579..1215958 (-)	1380	WP_002998058.1	hypothetical protein	-
DK182_RS06110 (DK181_06110)	topA	1216122..1218266 (-)	2145	WP_109833595.1	type I DNA topoisomerase	-
DK182_RS06115 (DK181_06115)	-	1218305..1218592 (+)	288	WP_019770717.1	hypothetical protein	-
DK182_RS06120 (DK181_06120)	dprA	1219243..1220082 (-)	840	WP_002962319.1	DNA-processing protein DprA	Machinery gene
DK182_RS06125 (DK181_06125)	-	1220291..1221778 (-)	1488	WP_019790038.1	ROK family protein	-
DK182_RS06130 (DK181_06130)	-	1221819..1222400 (-)	582	WP_109833596.1	DapH/DapD/GlmU-related protein	-
DK182_RS06135 (DK181_06135)	-	1222437..1223204 (-)	768	WP_019769339.1	ribonuclease HII	-
DK182_RS06140 (DK181_06140)	ylqF	1223191..1224042 (-)	852	WP_002962311.1	ribosome biogenesis GTPase YlqF	-
DK182_RS06145 (DK181_06145)	-	1224174..1224680 (-)	507	WP_002962309.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31264.91 Da
• Isoelectric Point: 7.4215

>NTDB_id=293217 DK182_RS06120 WP_002962319.1 1219243..1220082(-) (dprA) [Streptococcus sobrinus strain 10919]
MNNFELFKLKQAGLTNLQILNILDYRKEIGKSLSLRDMAVVSQTSKAGHFMETYKHLDLKDLRQQFNRFPSLSILDKEYP
EDLAQIYNPPVLLFYQGDLTLLDAPKLSLVGSRNCTQMGTKSVQKIIRNLENRFVIVSGLARGIDTAAHIACLKNGGKTI
AVVGTGLDVYYPKENRDLQDYLAKHHLVLSEYEPGQDPLKFHFPERNRIIAGLSRGTVVVQAKQRSGSLITCERAMEEGR
DVFAVPGNIIDGQSDGCHHLIQEGAKCIMTGQDILAEYE

Nucleotide

• Length: 840 bp

>NTDB_id=293217 DK182_RS06120 WP_002962319.1 1219243..1220082(-) (dprA) [Streptococcus sobrinus strain 10919]
ATGAATAATTTTGAACTCTTCAAGCTCAAACAGGCGGGCTTGACCAACCTGCAGATTCTTAATATCTTGGACTACCGGAA
GGAGATTGGTAAGTCCCTGTCCCTGCGGGATATGGCCGTAGTTTCCCAGACCAGCAAGGCCGGTCATTTTATGGAGACTT
ACAAGCACCTGGATCTCAAGGACTTGCGTCAGCAATTTAATCGTTTTCCTTCTCTTTCTATTTTGGATAAGGAATATCCC
GAGGATTTAGCTCAAATCTACAATCCTCCCGTTCTCCTCTTTTATCAGGGGGATTTAACGCTTCTGGATGCCCCAAAACT
TTCCCTAGTAGGTTCCAGAAATTGTACACAAATGGGAACCAAGTCAGTTCAGAAAATTATCCGCAACCTAGAAAATCGCT
TTGTCATCGTTTCTGGACTGGCAAGAGGAATTGATACTGCAGCCCACATTGCCTGTCTAAAAAATGGCGGTAAAACCATT
GCTGTTGTCGGGACCGGTTTGGATGTTTACTACCCAAAAGAAAACCGCGATCTGCAGGATTATTTGGCCAAGCACCACCT
AGTTTTGTCTGAATACGAGCCAGGACAAGACCCGCTCAAATTTCATTTTCCCGAACGCAATCGCATCATCGCGGGTCTCT
CAAGAGGAACAGTCGTGGTCCAAGCCAAGCAACGCTCGGGCAGTCTGATTACCTGCGAGCGGGCTATGGAGGAAGGACGG
GATGTCTTTGCGGTTCCCGGAAACATCATTGACGGTCAATCAGACGGCTGTCATCATCTCATTCAAGAGGGAGCCAAGTG
CATCATGACGGGCCAGGATATTCTGGCAGAATATGAGTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	74.101	99.642	0.738
dprA/cilB/dalA	Streptococcus mitis SK321	63.441	100	0.634
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.441	100	0.634
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.441	100	0.634
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.441	100	0.634
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.441	100	0.634
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.082	100	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	60.432	99.642	0.602
dprA	Legionella pneumophila strain ERS1305867	38.947	100	0.398
dprA	Acinetobacter baumannii D1279779	35.889	100	0.369
dprA	Bacillus subtilis subsp. subtilis str. 168	48.804	74.91	0.366