Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DK181_RS07860 Genome accession   NZ_CP029490
Coordinates   1628583..1629290 (-) Length   235 a.a.
NCBI ID   WP_002960995.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1623583..1634290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS07845 (DK182_07845) - 1624678..1626117 (+) 1440 WP_002961001.1 TrkH family potassium uptake protein -
  DK181_RS07850 (DK182_07850) vicX 1626427..1627236 (-) 810 WP_002960999.1 MBL fold metallo-hydrolase Regulator
  DK181_RS07855 (DK182_07855) vicK 1627229..1628590 (-) 1362 WP_002960997.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK181_RS07860 (DK182_07860) vicR 1628583..1629290 (-) 708 WP_002960995.1 response regulator YycF Regulator
  DK181_RS07865 (DK182_07865) - 1629516..1630280 (+) 765 WP_002960993.1 amino acid ABC transporter ATP-binding protein -
  DK181_RS07870 (DK182_07870) - 1630294..1631118 (+) 825 WP_002960992.1 transporter substrate-binding domain-containing protein -
  DK181_RS07875 (DK182_07875) - 1631134..1631841 (+) 708 WP_002960990.1 amino acid ABC transporter permease -
  DK181_RS07880 (DK182_07880) - 1631856..1632506 (+) 651 WP_002960988.1 amino acid ABC transporter permease -
  DK181_RS07885 (DK182_07885) - 1633130..1634035 (-) 906 WP_002960986.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27159.98 Da        Isoelectric Point: 4.7200

>NTDB_id=293172 DK181_RS07860 WP_002960995.1 1628583..1629290(-) (vicR) [Streptococcus sobrinus strain SL1]
MKKILVVDDEKPISDIIKFNLIKEGYEVVTAFDGKEALKRFDDENPDLIILDWMLPELEGLEVAKEIRKSSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTENIETAVAEENDASDSELTIGDLQIIPDAFVAKKRGEELEL
THREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=293172 DK181_RS07860 WP_002960995.1 1628583..1629290(-) (vicR) [Streptococcus sobrinus strain SL1]
ATGAAAAAGATTCTTGTTGTCGACGATGAAAAGCCGATTTCAGATATTATCAAGTTTAATTTAATTAAAGAAGGTTATGA
AGTAGTGACTGCCTTTGATGGTAAGGAAGCTTTGAAACGGTTTGACGATGAAAATCCAGATTTGATCATCTTGGACTGGA
TGTTGCCAGAATTGGAAGGCTTAGAAGTCGCTAAAGAAATTCGCAAGAGCAGCCATGTGCCAATCATTATGCTGTCTGCC
AAGGACAGTGAGTTCGATAAGGTTATTGGTTTGGAAATTGGTGCTGATGACTATGTCACCAAGCCTTTCTCTAATCGTGA
ACTTTTGGCTCGAATCAAGGCTCACCTGCGCCGAACTGAAAACATCGAGACAGCTGTTGCTGAAGAAAACGATGCCTCGG
ATAGCGAATTAACTATTGGAGACTTACAGATTATTCCTGATGCTTTTGTTGCCAAAAAACGCGGGGAAGAGTTGGAATTG
ACCCATCGTGAATTTGAACTCCTCCATCATCTGGCTACTCATATCGGTCAAGTAATGACCCGCGAGCACCTACTGGAAAC
TGTTTGGGGTTATGACTACTTTGGTGATGTCAGAACAGTCGATGTTACTATCAGACGTCTCCGTGAGAAAATTGAGGATA
CTCCAAGCCGACCAGAATATATTTTAACCCGTCGTGGCGTTGGTTATTATATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.234

100

0.872
  micA Streptococcus pneumoniae Cp1015

77.682

99.149

0.77
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

38.889

99.574

0.387

Multiple sequence alignment