Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DK181_RS07855 Genome accession   NZ_CP029490
Coordinates   1627229..1628590 (-) Length   453 a.a.
NCBI ID   WP_002960997.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1622229..1633590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS07840 (DK182_07840) trkA 1623318..1624667 (+) 1350 WP_002961003.1 Trk system potassium transporter TrkA -
  DK181_RS07845 (DK182_07845) - 1624678..1626117 (+) 1440 WP_002961001.1 TrkH family potassium uptake protein -
  DK181_RS07850 (DK182_07850) vicX 1626427..1627236 (-) 810 WP_002960999.1 MBL fold metallo-hydrolase Regulator
  DK181_RS07855 (DK182_07855) vicK 1627229..1628590 (-) 1362 WP_002960997.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK181_RS07860 (DK182_07860) vicR 1628583..1629290 (-) 708 WP_002960995.1 response regulator YycF Regulator
  DK181_RS07865 (DK182_07865) - 1629516..1630280 (+) 765 WP_002960993.1 amino acid ABC transporter ATP-binding protein -
  DK181_RS07870 (DK182_07870) - 1630294..1631118 (+) 825 WP_002960992.1 transporter substrate-binding domain-containing protein -
  DK181_RS07875 (DK182_07875) - 1631134..1631841 (+) 708 WP_002960990.1 amino acid ABC transporter permease -
  DK181_RS07880 (DK182_07880) - 1631856..1632506 (+) 651 WP_002960988.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 51804.28 Da        Isoelectric Point: 4.3498

>NTDB_id=293171 DK181_RS07855 WP_002960997.1 1627229..1628590(-) (vicK) [Streptococcus sobrinus strain SL1]
MNNNPVVENLNTFELALLILLALVALYFIYQAVREYRNAKTVRAISQKVTSLIAGDYTEDLHLKGDSELIELGTNLNDLS
DVLHLTHENLSQERNRLASVLSYMSDGVLATNRVGKITMINDTARKQLNLTREEALEMNIMDLIDSDDYDYRDLITQTPE
VTLYRRNEYDEFITLRVNFALNRRESGFISGLVAVLHDTTEQEKEERERRLFVSTVSHELRTPLTSVKSYLEALNEGALN
EEVAPSFIQVSLDETNRMMRMISDLLQLSRIDNDTSHIEVEMTNFTAFITVILNRFDQIKSQQDSDKDYEIVRNYPLNPI
WVEIDTDKMTQVLDNILNNAIKYSPDGGQITVSMTTTETQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLAIAKEIIKQHQGFIWAKSEYGKGSTFTIVLPYDKEPDDFDDEWEEDESVDD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=293171 DK181_RS07855 WP_002960997.1 1627229..1628590(-) (vicK) [Streptococcus sobrinus strain SL1]
ATGAATAATAATCCTGTTGTTGAAAATCTCAATACCTTTGAATTAGCCCTGCTCATTCTTTTGGCCCTAGTTGCCCTTTA
TTTTATTTATCAAGCAGTGCGGGAGTACCGCAATGCTAAGACCGTTCGTGCTATTAGCCAAAAGGTAACCAGCCTGATTG
CTGGTGATTACACGGAGGATCTTCACTTAAAAGGGGATTCTGAATTGATTGAGCTGGGGACCAACTTGAATGACCTGTCA
GATGTTTTGCATTTGACCCATGAAAATCTTTCACAAGAGCGCAATCGCCTAGCTTCCGTCCTGTCCTATATGAGTGATGG
GGTTTTAGCGACCAATCGGGTTGGAAAAATTACCATGATCAATGATACGGCCCGCAAGCAGCTCAATCTAACCCGAGAAG
AAGCGCTTGAGATGAACATCATGGATTTGATTGACTCAGATGACTATGATTATCGTGACTTGATTACCCAGACCCCCGAG
GTGACCCTCTATCGTCGCAATGAATACGATGAATTTATCACCTTGCGGGTCAATTTTGCCCTCAACCGTCGGGAGAGTGG
TTTTATTTCTGGTCTGGTTGCCGTTCTTCACGATACGACCGAACAGGAAAAGGAAGAGCGAGAACGCCGTCTCTTCGTCT
CGACCGTCAGTCATGAGTTGCGCACGCCGCTGACCTCGGTCAAGTCCTACCTAGAGGCCCTCAATGAAGGTGCCCTCAAT
GAAGAGGTGGCACCGAGCTTTATTCAGGTGTCCCTAGATGAGACCAATCGCATGATGCGGATGATTTCTGACCTCCTGCA
ATTATCGCGGATTGACAATGATACCAGCCATATTGAGGTCGAAATGACCAATTTTACGGCCTTTATTACGGTTATCCTGA
ATCGTTTTGACCAGATTAAGAGTCAGCAGGATTCCGACAAGGACTATGAAATTGTTCGCAACTATCCCTTGAATCCCATC
TGGGTTGAAATTGATACCGACAAGATGACCCAGGTGCTGGATAACATTCTCAACAATGCCATTAAATATTCACCAGACGG
TGGTCAAATTACCGTTTCAATGACAACCACAGAGACTCAGTTGATTATTTCCATTTCTGACCAAGGACTGGGGATTCCTA
AGAAGGACCTGCCTCTGATTTTTGACCGCTTCTACCGTGTTGATAAGGCCCGCAGTCGGGCCCAAGGTGGAACTGGTCTG
GGCTTGGCCATTGCTAAGGAAATTATTAAGCAACATCAGGGCTTTATCTGGGCCAAGAGCGAGTACGGTAAGGGTTCAAC
CTTTACCATTGTGCTTCCTTATGACAAGGAGCCTGATGATTTTGATGATGAATGGGAGGAAGATGAGTCCGTCGATGACT
AA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(97-161)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

91.391

0.68
  micB Streptococcus pneumoniae Cp1015

69.267

93.377

0.647

Multiple sequence alignment