Detailed information NTG0292271

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DF184_RS04280
• Genome accession: NZ_CP029398
• Coordinates: 847738..848409 (+)
• Length: 223 a.a.
• NCBI ID: WP_109371374.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HN105
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 842738..853409

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DF184_RS04250 (DF184_04250)	pstC	842921..843838 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
DF184_RS04255 (DF184_04255)	pstA	843828..844715 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
DF184_RS04260 (DF184_04260)	pstB	844740..845543 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
DF184_RS04265 (DF184_04265)	pstB	845555..846313 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
DF184_RS04270 (DF184_04270)	phoU	846342..846998 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
DF184_RS04275 (DF184_04275)	-	847164..847544 (+)	381	WP_024401461.1	hypothetical protein	-
DF184_RS04280 (DF184_04280)	ciaR	847738..848409 (+)	672	WP_109371374.1	response regulator transcription factor	Regulator
DF184_RS04285 (DF184_04285)	ciaH	848402..849781 (+)	1380	WP_024401460.1	HAMP domain-containing sensor histidine kinase	Regulator
DF184_RS04290 (DF184_04290)	-	849882..850964 (+)	1083	WP_239425124.1	transglutaminase domain-containing protein	-
DF184_RS11260	-	850983..851111 (+)	129	WP_275425326.1	hypothetical protein	-
DF184_RS04295 (DF184_04295)	rpsT	851339..851587 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
DF184_RS04300 (DF184_04300)	coaA	851646..852566 (-)	921	WP_002935283.1	type I pantothenate kinase	-
DF184_RS04305 (DF184_04305)	-	852675..853265 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25271.86 Da
• Isoelectric Point: 4.2183

>NTDB_id=292271 DF184_RS04280 WP_109371374.1 847738..848409(+) (ciaR) [Streptococcus suis strain HN105]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNP

Nucleotide

• Length: 672 bp

>NTDB_id=292271 DF184_RS04280 WP_109371374.1 847738..848409(+) (ciaR) [Streptococcus suis strain HN105]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTGGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGTATTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTTTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTGCCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATCCCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	89.686	100	0.897
ciaR	Streptococcus pneumoniae Rx1	89.189	99.552	0.888
ciaR	Streptococcus pneumoniae D39	89.189	99.552	0.888
ciaR	Streptococcus pneumoniae R6	89.189	99.552	0.888
ciaR	Streptococcus pneumoniae TIGR4	89.189	99.552	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368