Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DF184_RS04285 Genome accession   NZ_CP029398
Coordinates   848402..849781 (+) Length   459 a.a.
NCBI ID   WP_024401460.1    Uniprot ID   -
Organism   Streptococcus suis strain HN105     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 843402..854781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS04255 (DF184_04255) pstA 843828..844715 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  DF184_RS04260 (DF184_04260) pstB 844740..845543 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  DF184_RS04265 (DF184_04265) pstB 845555..846313 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  DF184_RS04270 (DF184_04270) phoU 846342..846998 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  DF184_RS04275 (DF184_04275) - 847164..847544 (+) 381 WP_024401461.1 hypothetical protein -
  DF184_RS04280 (DF184_04280) ciaR 847738..848409 (+) 672 WP_109371374.1 response regulator transcription factor Regulator
  DF184_RS04285 (DF184_04285) ciaH 848402..849781 (+) 1380 WP_024401460.1 HAMP domain-containing sensor histidine kinase Regulator
  DF184_RS04290 (DF184_04290) - 849882..850964 (+) 1083 WP_239425124.1 transglutaminase domain-containing protein -
  DF184_RS11260 - 850983..851111 (+) 129 WP_275425326.1 hypothetical protein -
  DF184_RS04295 (DF184_04295) rpsT 851339..851587 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  DF184_RS04300 (DF184_04300) coaA 851646..852566 (-) 921 WP_002935283.1 type I pantothenate kinase -
  DF184_RS04305 (DF184_04305) - 852675..853265 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  DF184_RS04310 (DF184_04310) - 853262..854539 (+) 1278 WP_024389005.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51862.42 Da        Isoelectric Point: 5.8702

>NTDB_id=292272 DF184_RS04285 WP_024401460.1 848402..849781(+) (ciaH) [Streptococcus suis strain HN105]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKETTVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=292272 DF184_RS04285 WP_024401460.1 848402..849781(+) (ciaH) [Streptococcus suis strain HN105]
ATCCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAACAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTTGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGTTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTACGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGTATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTGACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49

Multiple sequence alignment