Detailed information NTG0291156

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DEH83_RS01470
• Genome accession: NZ_CP029207
• Coordinates: 307307..308053 (+)
• Length: 248 a.a.
• NCBI ID: WP_255776891.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain TCV107
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 302307..313053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DEH83_RS01435 (DEH83_01410)	-	303529..303747 (-)	219	WP_021002958.1	Blp family class II bacteriocin	-
DEH83_RS01440 (DEH83_01415)	-	303922..304242 (-)	321	WP_049476579.1	hypothetical protein	-
DEH83_RS01445 (DEH83_01420)	-	304392..304682 (-)	291	WP_006267076.1	bacteriocin immunity protein	-
DEH83_RS01450 (DEH83_01425)	-	304734..304967 (-)	234	WP_003025420.1	garvicin Q family class II bacteriocin	-
DEH83_RS01455 (DEH83_01430)	-	304975..305295 (-)	321	WP_006267159.1	hypothetical protein	-
DEH83_RS01460 (DEH83_01440)	-	305972..306193 (-)	222	WP_006267535.1	Blp family class II bacteriocin	-
DEH83_RS01465 (DEH83_01445)	-	306425..307138 (+)	714	WP_020997680.1	CPBP family intramembrane glutamic endopeptidase	-
DEH83_RS01470 (DEH83_01450)	comE/blpR	307307..308053 (+)	747	WP_255776891.1	response regulator transcription factor	Regulator
DEH83_RS01475 (DEH83_01455)	-	308454..309365 (+)	912	WP_255776892.1	sensor histidine kinase	-
DEH83_RS01480 (DEH83_01460)	-	309410..309559 (-)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DEH83_RS01485 (DEH83_01465)	-	309653..311014 (-)	1362	WP_255776893.1	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 248 a.a.
• Molecular weight: 28735.15 Da
• Isoelectric Point: 7.0139

>NTDB_id=291156 DEH83_RS01470 WP_255776891.1 307307..308053(+) (comE/blpR) [Streptococcus constellatus strain TCV107]
MNIFILEDDLTQQYYMETIVEEIIEKHQLQYHHFEVVGKPKQLLEAISEKGSHQIFFLDIEIKTEEEKGLDVAKKIREID
PYAIIVFVTSHSELMPTAFKLQVGALDYLDKSLSKEIFKKRIETALLHTESLTGKGLADDALLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLLDILKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHRRE

Nucleotide

• Length: 747 bp

>NTDB_id=291156 DEH83_RS01470 WP_255776891.1 307307..308053(+) (comE/blpR) [Streptococcus constellatus strain TCV107]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAGAAATTATCGAAAAACA
TCAACTTCAATATCATCATTTTGAAGTTGTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGATTTTCTTTTTAGACATTGAAATCAAAACCGAGGAAGAAAAGGGCTTAGACGTTGCTAAAAAGATACGCGAGATAGAT
CCTTATGCCATCATTGTCTTTGTAACCAGTCATTCTGAATTGATGCCTACAGCGTTTAAGCTGCAAGTGGGTGCCCTTGA
TTATCTTGACAAATCGTTATCAAAAGAAATCTTTAAAAAACGGATCGAAACTGCACTGCTACATACTGAAAGCCTAACAG
GTAAAGGGCTGGCAGACGATGCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCATTTAAAGATATTCTTTAT
ATTGAAACTTCCTCTCGCCCTCACCGCTTAGTTCTTTACACACATAGAGGACGTACGGAATTTACTGCTAATCTTTTAGA
TATTTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGCTCCTTTGTTGTTAATCCAGCTAATGTCCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGTTAACAGAAGCC
ATTGCAGCCCTGCACCGGAGGGAATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	49.798	99.597	0.496
comE/comE1	Streptococcus equinus JB1	44.304	95.565	0.423
comE	Streptococcus pneumoniae Rx1	36.992	99.194	0.367
comE	Streptococcus pneumoniae D39	36.992	99.194	0.367
comE	Streptococcus pneumoniae R6	36.992	99.194	0.367
comE	Streptococcus pneumoniae TIGR4	36.992	99.194	0.367
comE	Streptococcus mitis NCTC 12261	36.992	99.194	0.367
comE	Streptococcus mitis SK321	36.992	99.194	0.367
comE	Streptococcus infantis strain Atu-4	36.585	99.194	0.363