Detailed information NTG0290759

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: C3363_RS03365
• Genome accession: NZ_CP029150
• Coordinates: 677943..679205 (+)
• Length: 420 a.a.
• NCBI ID: WP_026917118.1
• Uniprot ID: -
• Organism: Glaesserella parasuis strain GZ20170512
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 672943..684205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3363_RS03340 (C3363_03365)	-	673137..675692 (-)	2556	WP_159179850.1	penicillin-binding protein 1A	-
C3363_RS03345 (C3363_03370)	comA	675846..676523 (+)	678	WP_010785957.1	hypothetical protein	Machinery gene
C3363_RS03350 (C3363_03375)	comB	676499..677020 (+)	522	WP_010785956.1	hypothetical protein	Machinery gene
C3363_RS03355 (C3363_03380)	comC	677017..677547 (+)	531	WP_015940159.1	hypothetical protein	Machinery gene
C3363_RS03360 (C3363_03385)	comD	677592..677933 (+)	342	WP_232422128.1	hypothetical protein	Machinery gene
C3363_RS03365 (C3363_03390)	comE	677943..679205 (+)	1263	WP_026917118.1	type IV pilus secretin PilQ	Machinery gene
C3363_RS03370 (C3363_03395)	nusB	679284..679697 (+)	414	WP_010785952.1	transcription antitermination factor NusB	-
C3363_RS03375 (C3363_03400)	thiL	679706..680674 (+)	969	WP_021110497.1	thiamine-phosphate kinase	-
C3363_RS03380 (C3363_03405)	-	680677..681147 (+)	471	WP_005712497.1	phosphatidylglycerophosphatase A	-
C3363_RS03385 (C3363_03410)	-	681149..681778 (+)	630	WP_015940164.1	LysE family transporter	-
C3363_RS03390 (C3363_03415)	trxA	682075..682389 (+)	315	WP_015940165.1	thioredoxin	-
C3363_RS03395 (C3363_03420)	-	682934..683569 (+)	636	WP_234886074.1	IS256 family transposase, variant Zn-binding type	-
C3363_RS03400 (C3363_03425)	-	683773..684192 (-)	420	WP_005714137.1	hotdog fold thioesterase	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 47095.07 Da
• Isoelectric Point: 8.9232

>NTDB_id=290759 C3363_RS03365 WP_026917118.1 677943..679205(+) (comE) [Glaesserella parasuis strain GZ20170512]
MRYLFLLFFATFPVLANQQISLSIRNAPTAEIISYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSENGYLHFDDRSNSIIVKDSAASVK
NFTQLIESLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINSRVLHLELTALESENNIEIIASPRLLTTDKKPASIKQGTEIPYAMYSKKKEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQMNNMMATIDKQEINTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQNRDKISKREL
VIFVTPYIVKSEKMGAEKQK

Nucleotide

• Length: 1263 bp

>NTDB_id=290759 C3363_RS03365 WP_026917118.1 677943..679205(+) (comE) [Glaesserella parasuis strain GZ20170512]
ATGCGTTATTTATTCCTGCTATTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCACTTTCGATAAGAAATGC
CCCAACGGCAGAGATTATTAGTTATTTGGCGGAGGAAACTGGAAAGAATATTACAATTTCGGATGAAATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTAATAGAGTCTTTGACAAAAGGGCAAGGCAACT
TGCTATCAGAGAATGGTTATCTTCATTTTGATGATCGCAGTAATAGTATTATCGTCAAAGACAGTGCCGCCTCAGTTAAA
AACTTTACTCAACTTATCGAAAGCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACGATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGAAACTTAG
AGGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAATCCGTCCGCTTCCGTTGCCTTACAAATTGCC
GCTATCAACAGCCGTGTACTTCATTTAGAACTCACCGCATTAGAGAGCGAAAATAACATTGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAACCAGCGAGTATCAAACAAGGTACAGAGATTCCTTATGCAATGTACAGTAAGAAAAAGG
AAATCACCGATATTGAATTTCGTGAAGCGGTTTTGGGGCTAGAAGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGATCTTGCCATTAGCCAAAATTCGCCAAATAACCAGATGAACAATATGATGGCAACGATTGATAAACAAGAAATTAA
TACACAAGTCCTTGCTAAACACGGCGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTCCCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAACCGAGATAAAATCTCTAAACGGGAGCTG
GTTATTTTTGTTACGCCTTATATTGTAAAATCTGAAAAAATGGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (110-175)

• Bacterial type II and III secretion system protein (Secretin) (253-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Glaesserella parasuis strain SC1401	97.381	100	0.974
comE	Haemophilus influenzae Rd KW20	52.706	100	0.533
comE	Haemophilus influenzae 86-028NP	51.765	100	0.524
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	37.681	98.571	0.371
pilQ	Vibrio cholerae strain A1552	37.681	98.571	0.371
pilQ	Vibrio campbellii strain DS40M4	36.493	100	0.367