Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CBUD_RS10440 Genome accession   NC_009727
Coordinates   2064673..2065599 (+) Length   308 a.a.
NCBI ID   WP_011997412.1    Uniprot ID   A9KH16
Organism   Coxiella burnetii Dugway 5J108-111     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2059673..2070599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CBUD_RS10400 (CBUD_2087) - 2060264..2060536 (-) 273 WP_010957319.1 hypothetical protein -
  CBUD_RS10405 (CBUD_2089) - 2060728..2060982 (+) 255 WP_005769716.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
  CBUD_RS10410 (CBUD_2091) - 2060982..2061257 (+) 276 WP_005769718.1 Txe/YoeB family addiction module toxin -
  CBUD_RS10415 (CBUD_2090) - 2061230..2061715 (-) 486 WP_005769725.1 dihydrofolate reductase -
  CBUD_RS10420 (CBUD_2092) - 2061712..2062515 (-) 804 WP_011997410.1 epoxyqueuosine reductase QueH -
  CBUD_RS10425 (CBUD_2095) - 2062711..2062998 (+) 288 WP_005769730.1 acylphosphatase -
  CBUD_RS10430 (CBUD_2094) gmhB 2062974..2063528 (-) 555 WP_005769732.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
  CBUD_RS10435 (CBUD_2096) fmt 2063541..2064485 (-) 945 WP_010958586.1 methionyl-tRNA formyltransferase -
  CBUD_RS10440 (CBUD_2098) dprA 2064673..2065599 (+) 927 WP_011997412.1 DNA-processing protein DprA Machinery gene
  CBUD_RS10445 (CBUD_2099) - 2065596..2066075 (+) 480 WP_011997413.1 DUF494 domain-containing protein -
  CBUD_RS10450 (CBUD_2100) topA 2066078..2068375 (+) 2298 WP_005769743.1 type I DNA topoisomerase -
  CBUD_RS10455 (CBUD_2100a) - 2068382..2068552 (-) 171 WP_011997414.1 hypothetical protein -
  CBUD_RS10460 (CBUD_2102) purE 2068583..2069083 (+) 501 WP_005769750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  CBUD_RS10465 (CBUD_2103) - 2069086..2069646 (+) 561 WP_011997415.1 L-threonylcarbamoyladenylate synthase -
  CBUD_RS13370 - 2069696..2069815 (+) 120 Protein_2134 hypothetical protein -
  CBUD_RS10470 (CBUD_2104) - 2070089..2070229 (+) 141 WP_011997416.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 33038.26 Da        Isoelectric Point: 7.5121

>NTDB_id=28916 CBUD_RS10440 WP_011997412.1 2064673..2065599(+) (dprA) [Coxiella burnetii Dugway 5J108-111]
MQPPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRVALKAGGQTIAVLGSGLTNIYPRRHHRLAEQISQKGALVSEFPLTMPPLP
TNFPRRNRIISGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSTPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=28916 CBUD_RS10440 WP_011997412.1 2064673..2065599(+) (dprA) [Coxiella burnetii Dugway 5J108-111]
TTGCAACCTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGTGGCTTTAAAAGCAGGAGGCCAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCGAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCCCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCAGCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGTGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAACACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A9KH16

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

54.266

95.13

0.516
  dprA Vibrio cholerae strain A1552

48.829

97.078

0.474
  dprA Vibrio campbellii strain DS40M4

47.386

99.351

0.471
  dprA Glaesserella parasuis strain SC1401

45.277

99.675

0.451
  dprA Acinetobacter baumannii D1279779

44.369

95.13

0.422
  dprA Acinetobacter baumannii strain A118

43.878

95.455

0.419
  dprA Acinetobacter baylyi ADP1

42.953

96.753

0.416
  dprA Haemophilus influenzae Rd KW20

55.505

70.779

0.393

Multiple sequence alignment