Detailed information NTG0289005

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DBK22_RS12005
• Genome accession: NZ_CP028961
• Coordinates: 2429731..2430327 (+)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus velezensis strain SRCM102752
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2424731..2435327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DBK22_RS11990 (DBK22_02413)	-	2425402..2426871 (-)	1470	WP_043020619.1	glycoside hydrolase family 32 protein	-
DBK22_RS11995 (DBK22_02414)	-	2426886..2428118 (-)	1233	WP_012118526.1	MFS transporter	-
DBK22_RS12000 (DBK22_02415)	-	2428509..2429483 (+)	975	WP_160242326.1	LacI family DNA-binding transcriptional regulator	-
DBK22_RS12005 (DBK22_02416)	clpP	2429731..2430327 (+)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
DBK22_RS12010 (DBK22_02417)	-	2430371..2431231 (-)	861	WP_076424587.1	LysR family transcriptional regulator	-
DBK22_RS12015 (DBK22_02418)	-	2431405..2432535 (+)	1131	WP_160242327.1	2-methylaconitate cis-trans isomerase PrpF family protein	-
DBK22_RS12020 (DBK22_02419)	-	2432579..2433955 (+)	1377	WP_061581243.1	MFS transporter	-
DBK22_RS12025 (DBK22_02420)	-	2434198..2434773 (-)	576	WP_015240657.1	TIGR00730 family Rossman fold protein	-
DBK22_RS12030 (DBK22_02421)	-	2434889..2435209 (+)	321	WP_003151506.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=289005 DBK22_RS12005 WP_003151513.1 2429731..2430327(+) (clpP) [Bacillus velezensis strain SRCM102752]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=289005 DBK22_RS12005 WP_003151513.1 2429731..2430327(+) (clpP) [Bacillus velezensis strain SRCM102752]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTATATTAACAGCCCTGGCGGATCAATCACTGCCGGTATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CAGAAATTGAAATCGCGGCAAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535