Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   EGX80_RS02560 Genome accession   NZ_CP033815
Coordinates   449260..449442 (-) Length   60 a.a.
NCBI ID   WP_011054856.1    Uniprot ID   A0A0H2UW47
Organism   Streptococcus pyogenes strain FDAARGOS_514     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 444260..454442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX80_RS02535 (EGX80_02535) ftsL 445194..445517 (-) 324 WP_002988895.1 cell division protein FtsL -
  EGX80_RS02540 (EGX80_02540) rsmH 445522..446472 (-) 951 WP_002988893.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  EGX80_RS10050 - 446559..446723 (-) 165 WP_002994245.1 hypothetical protein -
  EGX80_RS02545 (EGX80_02545) - 446825..446986 (-) 162 WP_159316501.1 hypothetical protein -
  EGX80_RS02550 (EGX80_02550) - 447006..448256 (-) 1251 WP_011054854.1 glutamate-5-semialdehyde dehydrogenase -
  EGX80_RS02555 (EGX80_02555) proB 448249..449070 (-) 822 WP_011054855.1 glutamate 5-kinase -
  EGX80_RS02560 (EGX80_02560) prx 449260..449442 (-) 183 WP_011054856.1 hypothetical protein Regulator
  EGX80_RS02565 (EGX80_02565) - 449675..450661 (+) 987 WP_011106647.1 DNA/RNA non-specific endonuclease -
  EGX80_RS02570 (EGX80_02570) - 450775..451290 (-) 516 WP_023077389.1 hypothetical protein -
  EGX80_RS02575 (EGX80_02575) - 451612..452814 (-) 1203 WP_149031611.1 glucosaminidase domain-containing protein -
  EGX80_RS02580 (EGX80_02580) - 452930..453157 (-) 228 WP_003058873.1 phage holin -
  EGX80_RS02585 (EGX80_02585) - 453154..453426 (-) 273 WP_002986916.1 hypothetical protein -
  EGX80_RS02590 (EGX80_02590) - 453436..454053 (-) 618 WP_011184056.1 DUF1366 domain-containing protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6927.67 Da        Isoelectric Point: 3.9286

>NTDB_id=284782 EGX80_RS02560 WP_011054856.1 449260..449442(-) (prx) [Streptococcus pyogenes strain FDAARGOS_514]
MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYALPNEEVRNGEVVTYENVEEVLRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=284782 EGX80_RS02560 WP_011054856.1 449260..449442(-) (prx) [Streptococcus pyogenes strain FDAARGOS_514]
ATGCTAACATACGATGAGTTTAAGCAAGCTATTGATGACGGATATATCACAGGCGACACAGTGGCGATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGCGTTGCCGAATGAAGAGGTAAGAAATGGGGAGGTTGTAACATACGAAAATGTGGAAGAAG
TGCTGAGGGAATTAGACAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UW47

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1
  prx Streptococcus pyogenes MGAS8232

80

100

0.8
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783
  prx Streptococcus pyogenes MGAS315

75

100

0.75
  prx Streptococcus pyogenes MGAS315

88.372

71.667

0.633
  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6
  prx Streptococcus pyogenes MGAS315

76.19

70

0.533