Detailed information NTG0284716

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SK637_RS06455
• Genome accession: NZ_CP028415
• Coordinates: 1245333..1245923 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613475.1
• Uniprot ID: F9HD24
• Organism: Streptococcus mitis strain SK637
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1240333..1250923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SK637_RS06425 (SK637_01255)	-	1241029..1241793 (-)	765	WP_033689032.1	ABC transporter ATP-binding protein	-
SK637_RS06430 (SK637_01256)	-	1241793..1242749 (-)	957	WP_033689033.1	branched-chain amino acid ABC transporter permease	-
SK637_RS06435 (SK637_01257)	-	1242753..1243622 (-)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
SK637_RS06440 (SK637_01258)	-	1243739..1244899 (-)	1161	WP_033689034.1	ABC transporter substrate-binding protein	-
SK637_RS06445 (SK637_01259)	-	1244966..1245253 (-)	288	WP_033689035.1	YlbG family protein	-
SK637_RS06455 (SK637_01260)	clpP	1245333..1245923 (-)	591	WP_000613475.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
SK637_RS06460 (SK637_01261)	-	1246047..1246400 (-)	354	WP_033689036.1	hypothetical protein	-
SK637_RS06465 (SK637_01262)	upp	1246425..1247054 (-)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
SK637_RS06470 (SK637_01263)	-	1247143..1247610 (-)	468	WP_000136976.1	deoxycytidylate deaminase	-
SK637_RS06475 (SK637_01264)	-	1247628..1248185 (-)	558	WP_033689037.1	TetR/AcrR family transcriptional regulator	-
SK637_RS06480 (SK637_01265)	-	1248310..1249155 (+)	846	WP_033689038.1	DegV family protein	-
SK637_RS06485 (SK637_01266)	-	1249213..1250385 (+)	1173	WP_033689039.1	NAD(P)/FAD-dependent oxidoreductase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21340.32 Da
• Isoelectric Point: 4.4910

>NTDB_id=284716 SK637_RS06455 WP_000613475.1 1245333..1245923(-) (clpP) [Streptococcus mitis strain SK637]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=284716 SK637_RS06455 WP_000613475.1 1245333..1245923(-) (clpP) [Streptococcus mitis strain SK637]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGCCCAGTTGAAGACAACATGGCCAACTCAGTTATTGCCCAGTTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGGGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACTATGAAC
TTTATCAAGGCTGATGTCCAAACTATCGTTATGGGGATGGCTGCATCTATGGGGACAGTTATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAGTACATGATTCACCAACCAATGGGGGGTACAGGTGGTGGTACTCAACAAA
CCGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCCCAAGAAACACTCGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: F9HD24

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	99.49	100	0.995
clpP	Streptococcus pneumoniae D39	99.49	100	0.995
clpP	Streptococcus pneumoniae R6	99.49	100	0.995
clpP	Streptococcus pneumoniae TIGR4	99.49	100	0.995
clpP	Streptococcus thermophilus LMG 18311	93.333	99.49	0.929
clpP	Streptococcus thermophilus LMD-9	93.333	99.49	0.929
clpP	Streptococcus pyogenes JRS4	91.282	99.49	0.908
clpP	Streptococcus pyogenes MGAS315	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	86.224	100	0.862
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571