Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SK637_RS05425 Genome accession   NZ_CP028415
Coordinates   1040606..1041313 (-) Length   235 a.a.
NCBI ID   WP_033688868.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1035606..1046313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS05405 (SK637_01055) - 1037211..1037558 (+) 348 WP_023944304.1 thioredoxin -
  SK637_RS05410 (SK637_01056) - 1037594..1038367 (-) 774 WP_033688865.1 potassium channel family protein -
  SK637_RS05415 (SK637_01057) vicX 1038453..1039262 (-) 810 WP_033688866.1 MBL fold metallo-hydrolase Regulator
  SK637_RS05420 (SK637_01058) micB 1039255..1040613 (-) 1359 WP_033688867.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SK637_RS05425 (SK637_01059) micA 1040606..1041313 (-) 708 WP_033688868.1 response regulator YycF Regulator
  SK637_RS05430 (SK637_01060) mutY 1041369..1042544 (-) 1176 WP_033688869.1 A/G-specific adenine glycosylase -
  SK637_RS05435 (SK637_01061) pta 1042778..1043752 (-) 975 WP_033688870.1 phosphate acetyltransferase -
  SK637_RS05440 (SK637_01062) - 1043796..1044692 (-) 897 WP_033688871.1 RluA family pseudouridine synthase -
  SK637_RS05445 (SK637_01063) - 1044689..1045507 (-) 819 WP_000799056.1 NAD kinase -
  SK637_RS05450 (SK637_01064) - 1045491..1046162 (-) 672 WP_033688872.1 GTP pyrophosphokinase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27007.78 Da        Isoelectric Point: 4.6664

>NTDB_id=284712 SK637_RS05425 WP_033688868.1 1040606..1041313(-) (micA) [Streptococcus mitis strain SK637]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFGAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASVDNQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=284712 SK637_RS05425 WP_033688868.1 1040606..1041313(-) (micA) [Streptococcus mitis strain SK637]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAACATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAACAATTTGGAGCAGAGCAGCCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCGAAGACTATTCGCAAGACTAGTAGTGTACCTATTATCATGCTGTCGGCT
AAAGACAGTGAGTTTGATAAGGTTATCGGTTTAGAGCTTGGAGCGGATGACTATGTGACAAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTTCGTCGCACGGACTTGGCTTCTGTAGACAATCAAGAGTCAGATGAAAAGAAAA
CCCAACCCTTACAAATTGGGGACTTGGAGATTGTGCCAGATGCTTATGTAGCTAAAAAATACGGTGAAGAATTAGACTTA
ACCCACCGTGAATTTGAACTCTTGTACCACTTGGCATCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAAAC
GGTCTGGGGTTATGATTATTTCGGAGATGTTCGGACTGTTGACGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGATA
CACCTAGTCGTCCAGAGTATATCTTAACACGTCGTGGTGTTGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

93.59

99.574

0.932
  vicR Streptococcus mutans UA159

77.021

100

0.77
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

38.462

99.574

0.383

Multiple sequence alignment