Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SK637_RS05420 Genome accession   NZ_CP028415
Coordinates   1039255..1040613 (-) Length   452 a.a.
NCBI ID   WP_033688867.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1034255..1045613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS05400 (SK637_01054) - 1035381..1037099 (+) 1719 WP_033688864.1 phospho-sugar mutase -
  SK637_RS05405 (SK637_01055) - 1037211..1037558 (+) 348 WP_023944304.1 thioredoxin -
  SK637_RS05410 (SK637_01056) - 1037594..1038367 (-) 774 WP_033688865.1 potassium channel family protein -
  SK637_RS05415 (SK637_01057) vicX 1038453..1039262 (-) 810 WP_033688866.1 MBL fold metallo-hydrolase Regulator
  SK637_RS05420 (SK637_01058) micB 1039255..1040613 (-) 1359 WP_033688867.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SK637_RS05425 (SK637_01059) micA 1040606..1041313 (-) 708 WP_033688868.1 response regulator YycF Regulator
  SK637_RS05430 (SK637_01060) mutY 1041369..1042544 (-) 1176 WP_033688869.1 A/G-specific adenine glycosylase -
  SK637_RS05435 (SK637_01061) pta 1042778..1043752 (-) 975 WP_033688870.1 phosphate acetyltransferase -
  SK637_RS05440 (SK637_01062) - 1043796..1044692 (-) 897 WP_033688871.1 RluA family pseudouridine synthase -
  SK637_RS05445 (SK637_01063) - 1044689..1045507 (-) 819 WP_000799056.1 NAD kinase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51903.41 Da        Isoelectric Point: 4.7330

>NTDB_id=284711 SK637_RS05420 WP_033688867.1 1039255..1040613(-) (micB) [Streptococcus mitis strain SK637]
MIELIRKNILTSDFIFILILLGFILIVTLLLLENRRDNIRLKQINQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGKITMINDMAKKQLGVEKEEVLNKSILELLKIEDEYELRDLITQVPE
LMIDSQDANGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDQIRGQDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEIENQNE

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=284711 SK637_RS05420 WP_033688867.1 1039255..1040613(-) (micB) [Streptococcus mitis strain SK637]
ATGATTGAATTGATTAGAAAAAATATTCTTACTAGTGATTTTATCTTCATTTTAATTTTATTGGGTTTTATCTTGATTGT
TACCTTGCTTTTGCTAGAAAATCGGCGAGATAATATTCGGTTGAAGCAAATTAATCAAAAAGTCAAAGATTTGATTGCAG
GAGATTATTCTCAGGTATTGGATATGCAGGGAAGCTCTGAAATCACTAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATTCGCTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGCACAGTATCCTCTCATACATGACAGACGGAGT
CCTTGCGACCAATCGTCGTGGCAAGATTACTATGATTAATGACATGGCTAAGAAACAGCTAGGTGTTGAGAAGGAAGAGG
TTCTCAATAAAAGTATTCTAGAATTGCTTAAGATTGAAGATGAGTATGAACTTCGTGATTTGATTACCCAAGTTCCTGAG
CTTATGATTGATTCTCAGGATGCCAATGGTGAGTATTTGAGCCTTCGTGTACGTTTTGCCTTGGTCCGTCGTGAGTCTGG
CTTTATCTCAGGTTTGGTTGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGGGAACGGAGACTCTTTGTTT
CTAATGTTAGTCATGAGTTACGAACTCCTTTGACTAGCGTAAAATCCTATCTTGAAGCTTTGGATGAGGGGGCCTTGTCA
GAACCTGTCGCGCCAGACTTTATTAAGGTGTCTCTAGATGAAACCAACCGTATGATGAGGATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCAACCAGTCACCTAGATGTGGAATTGATCAATTTCACTGCCTTTATTACCTTTATCCTCA
ACCGTTTTGATCAGATAAGAGGGCAGGACGAAGAGAAGAAATACGAACTGGTGAGAGATTACCCCATTACCTCAGTTTGG
ATAGAGATTGATACAGATAAGATGACACAGGTGATTGATAATATTCTTAACAATGCAATCAAGTATTCTCCAGATGGTGG
GAAAATCACAGTGACCATGAAGACAACTGATGATCAGATGATTTTATCCATTTCAGACCAAGGATTGGGGATACCAAAGC
AAGATTTACCACGTATCTTTGACCGTTTTTATCGTGTGGATCGTGCTAGAAGTCGTGCCCAAGGTGGTACTGGTTTAGGA
CTAGCTATCGCTAAAGAGATTATCAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAATATGGTAAGGGATCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGACGAAATAGAAAACCAGAATGAGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.749

97.124

0.872
  vicK Streptococcus mutans UA159

73.134

88.938

0.65

Multiple sequence alignment