Detailed information NTG0284706

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: SK637_RS04295
• Genome accession: NZ_CP028415
• Coordinates: 784618..785268 (+)
• Length: 216 a.a.
• NCBI ID: WP_033688715.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain SK637
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 779618..790268

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SK637_RS04265 (SK637_00833)	pyrH	780241..780978 (+)	738	WP_033688711.1	UMP kinase	-
SK637_RS04270 (SK637_00834)	frr	780987..781544 (+)	558	WP_001262225.1	ribosome recycling factor	-
SK637_RS04275 (SK637_00835)	cvfB	781604..782458 (+)	855	WP_033688712.1	RNA-binding virulence regulatory protein CvfB	-
SK637_RS04280 (SK637_00836)	-	782466..782681 (+)	216	WP_001232084.1	YozE family protein	-
SK637_RS04285 (SK637_00837)	-	782766..783770 (+)	1005	WP_033688713.1	PhoH family protein	-
SK637_RS04290 (SK637_00838)	-	783982..784551 (+)	570	WP_033688714.1	GNAT family N-acetyltransferase	-
SK637_RS04295 (SK637_00839)	comEA/celA/cilE	784618..785268 (+)	651	WP_033688715.1	helix-hairpin-helix domain-containing protein	Machinery gene
SK637_RS04300 (SK637_00840)	comEC/celB	785252..787492 (+)	2241	WP_033688716.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SK637_RS10105	-	787634..787858 (+)	225	WP_033688717.1	hypothetical protein	-
SK637_RS04310 (SK637_00841)	-	787891..788478 (+)	588	WP_033688718.1	ATP-binding cassette domain-containing protein	-
SK637_RS04315 (SK637_00842)	-	788482..789666 (+)	1185	WP_033688719.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23178.61 Da
• Isoelectric Point: 6.5093

>NTDB_id=284706 SK637_RS04295 WP_033688715.1 784618..785268(+) (comEA/celA/cilE) [Streptococcus mitis strain SK637]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPHIPVKETNLQAEVAAVSKDSLTEKEVKKEEKEEPIEQDLITVDVKG
AVKAPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAASQQAGSGAPSSTSKEKKLNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=284706 SK637_RS04295 WP_033688715.1 784618..785268(+) (comEA/celA/cilE) [Streptococcus mitis strain SK637]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATCTGTACTGGTCTAGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACACATACCTGTCAAAGAAACGAATTTGCAGGCAGAAGTTGCAGCTGTTTCCAAGGATT
CATTAACCGAAAAGGAAGTGAAGAAGGAAGAAAAAGAAGAACCTATTGAACAAGATCTAATCACAGTAGATGTGAAAGGA
GCTGTTAAAGCACCAGGAATTTATGATTTGCCGGTAGGTAGCAGAGTCAATGACGCTGTTCAGAAGGCTGGTGGGTTGAC
AGAGCAAGCCGACAGCAAGTCACTCAATCTAGCTCAGAAAGTTAGTGACGAGGCTCTGGTTTACGTTCCCACTAAGGGAG
AAGAAGCAGCTAGTCAACAGGCAGGTTCTGGAGCGCCTTCTTCAACAAGCAAGGAAAAGAAGCTCAATCTCAACAAGGCC
AGTCTGGAAGAACTTAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGATCATCGTGAGGCAAATGG
GAAATTCAAGTCGGTCGATGAACTCAAGAAAGTATCTGGCATTGGTGCCAAGACAATAGAAAAGCTAAAAGATTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	94.907	100	0.949
comEA/celA/cilE	Streptococcus mitis NCTC 12261	94.907	100	0.949
comEA/celA/cilE	Streptococcus mitis SK321	93.519	100	0.935
comEA/celA/cilE	Streptococcus pneumoniae Rx1	92.593	100	0.926
comEA/celA/cilE	Streptococcus pneumoniae D39	92.593	100	0.926
comEA/celA/cilE	Streptococcus pneumoniae R6	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	40.969	100	0.431
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361