Detailed information NTG0283335

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: C7M29_RS08390
• Genome accession: NZ_CP028217
• Coordinates: 1622333..1622926 (-)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain SRCM102751
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1617333..1627926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M29_RS08375 (C7M29_01647)	mdxK	1617648..1619921 (+)	2274	WP_161476677.1	maltose phosphorylase	-
C7M29_RS08380 (C7M29_01648)	malL	1619914..1621599 (+)	1686	WP_128993442.1	oligo-1,6-glucosidase	-
C7M29_RS08385 (C7M29_01649)	pgmB	1621596..1622270 (+)	675	WP_048655002.1	beta-phosphoglucomutase	-
C7M29_RS08390 (C7M29_01650)	clpP	1622333..1622926 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
C7M29_RS08400 (C7M29_01652)	cotR	1623555..1624517 (-)	963	WP_015251166.1	sporulation hydrolase CotR	-
C7M29_RS08405 (C7M29_01653)	cotNP	1624874..1626217 (+)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
C7M29_RS08410 (C7M29_01654)	yvdQ	1626469..1626981 (+)	513	WP_080529823.1	DUF3231 family protein	-
C7M29_RS08415 (C7M29_01655)	psmB	1627017..1627337 (-)	321	WP_076457550.1	multidrug efflux SMR transporter	-
C7M29_RS08420 (C7M29_01656)	psmA	1627337..1627672 (-)	336	WP_003242480.1	SMR family transporter	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=283335 C7M29_RS08390 WP_003228214.1 1622333..1622926(-) (clpP) [Bacillus subtilis strain SRCM102751]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=283335 C7M29_RS08390 WP_003228214.1 1622333..1622926(-) (clpP) [Bacillus subtilis strain SRCM102751]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGAATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538