Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   EB818_RS05080 Genome accession   NZ_CP033335
Coordinates   981204..981392 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A0H2UUN1
Organism   Streptococcus pyogenes strain TSPY208     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 976204..986392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS05055 (EB818_05065) - 978004..978375 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  EB818_RS05060 (EB818_05070) - 978375..979073 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  EB818_RS05065 (EB818_05075) - 979083..979868 (+) 786 WP_129322706.1 ABC transporter permease -
  EB818_RS05070 (EB818_05080) - 979999..980613 (-) 615 WP_129322707.1 TVP38/TMEM64 family protein -
  EB818_RS05080 (EB818_05090) prx 981204..981392 (-) 189 WP_011054546.1 hypothetical protein Regulator
  EB818_RS05085 (EB818_05095) spel 981507..982295 (-) 789 WP_021340779.1 streptococcal pyrogenic exotoxin SpeL -
  EB818_RS05090 (EB818_05100) spem 982577..983257 (-) 681 WP_129322708.1 streptococcal pyrogenic exotoxin SpeM -
  EB818_RS05095 (EB818_05105) - 983226..983750 (-) 525 WP_129322709.1 type II toxin-antitoxin system antitoxin SocA domain-containing protein -
  EB818_RS05100 (EB818_05110) - 983889..985097 (-) 1209 WP_012560948.1 glucosaminidase domain-containing protein -
  EB818_RS05105 (EB818_05115) - 985145..985918 (-) 774 Protein_928 terminase large subunit -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=282992 EB818_RS05080 WP_011054546.1 981204..981392(-) (prx) [Streptococcus pyogenes strain TSPY208]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=282992 EB818_RS05080 WP_011054546.1 981204..981392(-) (prx) [Streptococcus pyogenes strain TSPY208]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UUN1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806

  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79

  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774

  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742

  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581

  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516


Multiple sequence alignment