Detailed information NTG0282860

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: C7M23_RS06980
• Genome accession: NZ_CP028209
• Coordinates: 1349068..1349661 (-)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain SRCM102745
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1344068..1354661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M23_RS06965 (C7M23_01369)	mdxK	1344402..1346675 (+)	2274	WP_131228137.1	maltose phosphorylase	-
C7M23_RS06970 (C7M23_01370)	malL	1346668..1348353 (+)	1686	WP_131228136.1	oligo-1,6-glucosidase	-
C7M23_RS06975 (C7M23_01371)	pgmB	1348350..1349024 (+)	675	WP_131228135.1	beta-phosphoglucomutase	-
C7M23_RS06980 (C7M23_01372)	clpP	1349068..1349661 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
C7M23_RS06990 (C7M23_01374)	cotR	1350290..1351252 (-)	963	WP_003243674.1	sporulation hydrolase CotR	-
C7M23_RS06995 (C7M23_01375)	cotNP	1351608..1352951 (+)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
C7M23_RS07000 (C7M23_01376)	yvdQ	1353203..1353715 (+)	513	WP_106073377.1	DUF3231 family protein	-
C7M23_RS07005 (C7M23_01377)	psmB	1353751..1354071 (-)	321	WP_076457550.1	multidrug efflux SMR transporter	-
C7M23_RS07010 (C7M23_01378)	psmA	1354071..1354406 (-)	336	WP_131228134.1	multidrug efflux SMR transporter	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=282860 C7M23_RS06980 WP_003228214.1 1349068..1349661(-) (clpP) [Bacillus subtilis strain SRCM102745]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=282860 C7M23_RS06980 WP_003228214.1 1349068..1349661(-) (clpP) [Bacillus subtilis strain SRCM102745]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGTGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538