Detailed information NTG0282449

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: C7M17_RS19130
• Genome accession: NZ_CP028202
• Coordinates: 3670958..3671551 (-)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain SRCM102754
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3665958..3676551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M17_RS19115 (C7M17_03773)	mdxK	3666273..3668546 (+)	2274	WP_160245587.1	maltose phosphorylase	-
C7M17_RS19120 (C7M17_03774)	malL	3668539..3670224 (+)	1686	WP_160245503.1	oligo-1,6-glucosidase	-
C7M17_RS19125 (C7M17_03775)	pgmB	3670221..3670895 (+)	675	WP_160245504.1	beta-phosphoglucomutase	-
C7M17_RS19130 (C7M17_03776)	clpP	3670958..3671551 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
C7M17_RS19140 (C7M17_03778)	yvdQ	3672052..3672564 (+)	513	WP_120027521.1	DUF3231 family protein	-
C7M17_RS19145 (C7M17_03779)	psmB	3672600..3672920 (-)	321	WP_122894746.1	multidrug efflux SMR transporter	-
C7M17_RS19150 (C7M17_03780)	psmA	3672920..3673255 (-)	336	WP_015483731.1	QacE family quaternary ammonium compound efflux SMR transporter	-
C7M17_RS19155 (C7M17_03781)	-	3673337..3673921 (-)	585	WP_183163631.1	TetR family transcriptional regulator	-
C7M17_RS19160 (C7M17_03782)	aspP	3674016..3675578 (-)	1563	WP_003228228.1	aspartate/proton symporter AspP	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=282449 C7M17_RS19130 WP_003228214.1 3670958..3671551(-) (clpP) [Bacillus subtilis strain SRCM102754]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=282449 C7M17_RS19130 WP_003228214.1 3670958..3671551(-) (clpP) [Bacillus subtilis strain SRCM102754]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCTTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538