Detailed information NTG0281592

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: C5P47_RS04595
• Genome accession: NZ_CP028140
• Coordinates: 889068..889904 (+)
• Length: 278 a.a.
• NCBI ID: WP_032464378.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS979
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 884068..894904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5P47_RS04565 (C5P47_04545)	-	884556..884990 (+)	435	WP_110410792.1	hypothetical protein	-
C5P47_RS04570 (C5P47_04550)	-	885040..885951 (-)	912	WP_031488278.1	diacylglycerol kinase family protein	-
C5P47_RS04575 (C5P47_04555)	-	886068..886718 (-)	651	WP_032464375.1	hemolysin III family protein	-
C5P47_RS04580 (C5P47_04560)	-	886715..887155 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
C5P47_RS04585 (C5P47_04565)	ylqF	887374..888222 (+)	849	WP_032464376.1	ribosome biogenesis GTPase YlqF	-
C5P47_RS04590 (C5P47_04570)	-	888212..889003 (+)	792	WP_032464377.1	ribonuclease HII	-
C5P47_RS04595 (C5P47_04575)	dprA	889068..889904 (+)	837	WP_032464378.1	DNA-processing protein DprA	Machinery gene
C5P47_RS04600 (C5P47_04580)	topA	890011..892140 (+)	2130	WP_032464379.1	type I DNA topoisomerase	-
C5P47_RS04605 (C5P47_04585)	trmFO	892275..893621 (+)	1347	WP_110410793.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31088.08 Da
• Isoelectric Point: 9.0513

>NTDB_id=281592 C5P47_RS04595 WP_032464378.1 889068..889904(+) (dprA) [Streptococcus pyogenes strain NGAS979]
MNHFELYKLKKARLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=281592 C5P47_RS04595 WP_032464378.1 889068..889904(+) (dprA) [Streptococcus pyogenes strain NGAS979]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTAGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Acinetobacter baumannii strain A118	35.395	100	0.371
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367