Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   C7K40_RS01520 Genome accession   NZ_CP027771
Coordinates   278594..279145 (+) Length   183 a.a.
NCBI ID   WP_080465145.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain DMG1800716     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 273594..284145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K40_RS01520 (C7K40_01520) comX/sigX/comX2/sigX2 278594..279145 (+) 552 WP_080465145.1 sigma-70 family RNA polymerase sigma factor Regulator
  C7K40_RS01525 (C7K40_01525) truA 279332..280081 (+) 750 WP_063629653.1 tRNA pseudouridine(38-40) synthase TruA -
  C7K40_RS01530 (C7K40_01530) - 280071..280835 (+) 765 WP_009880948.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  C7K40_RS01535 (C7K40_01535) - 280825..281295 (+) 471 WP_002988139.1 ECF transporter S component -
  C7K40_RS01540 (C7K40_01540) - 281309..281869 (+) 561 WP_063629654.1 TIGR01440 family protein -
  C7K40_RS01545 (C7K40_01545) - 281934..282779 (-) 846 WP_002982833.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22309.13 Da        Isoelectric Point: 10.0375

>NTDB_id=280439 C7K40_RS01520 WP_080465145.1 278594..279145(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain DMG1800716]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIVSLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=280439 C7K40_RS01520 WP_080465145.1 278594..279145(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain DMG1800716]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATTTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGTTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment