Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   SSA_RS08410 Genome accession   NC_009009
Coordinates   1716308..1716925 (-) Length   205 a.a.
NCBI ID   WP_223311179.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1703718..1716898 1716308..1716925 flank -590


Gene organization within MGE regions


Location: 1703718..1716925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS08335 - 1703718..1704248 (-) 531 WP_002897081.1 hypothetical protein -
  SSA_RS08340 (SSA_1717) - 1704245..1705048 (-) 804 WP_011837305.1 DNA-methyltransferase -
  SSA_RS08345 (SSA_1718) - 1705041..1705901 (-) 861 WP_011837306.1 DNA adenine methylase -
  SSA_RS08350 (SSA_1719) rsmI 1706014..1706883 (-) 870 WP_011837307.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  SSA_RS08355 (SSA_1720) yabA 1706886..1707203 (-) 318 WP_002909165.1 DNA replication initiation control protein YabA -
  SSA_RS08360 (SSA_1721) - 1707228..1708118 (-) 891 WP_011837308.1 DNA polymerase III subunit delta' -
  SSA_RS08365 (SSA_1722) tmk 1708115..1708753 (-) 639 WP_002923625.1 dTMP kinase -
  SSA_RS08370 (SSA_1723) - 1709066..1709953 (+) 888 WP_011837309.1 YitT family protein -
  SSA_RS08375 (SSA_1724) - 1709987..1710643 (-) 657 WP_011837310.1 CBS domain-containing protein -
  SSA_RS08380 (SSA_1725) - 1711083..1711793 (-) 711 WP_002894681.1 ABC transporter ATP-binding protein -
  SSA_RS08385 (SSA_1726) - 1711793..1712557 (-) 765 WP_011837311.1 ABC transporter ATP-binding protein -
  SSA_RS08390 (SSA_1727) - 1712557..1713510 (-) 954 WP_011837312.1 branched-chain amino acid ABC transporter permease -
  SSA_RS08395 (SSA_1728) - 1713514..1714383 (-) 870 WP_002897070.1 branched-chain amino acid ABC transporter permease -
  SSA_RS08400 (SSA_1729) - 1714629..1715789 (-) 1161 WP_011837313.1 ABC transporter substrate-binding protein -
  SSA_RS08405 (SSA_1730) - 1715878..1716147 (-) 270 WP_002894676.1 YlbG family protein -
  SSA_RS08410 (SSA_1731) clpP 1716308..1716925 (-) 618 WP_223311179.1 ATP-dependent Clp protease proteolytic subunit Regulator

Sequence

Protein


Download         Length: 205 a.a.        Molecular weight: 22726.96 Da        Isoelectric Point: 4.7792

>NTDB_id=27531 SSA_RS08410 WP_223311179.1 1716308..1716925(-) (clpP) [Streptococcus sanguinis SK36]
MLKREREKTMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSA
GLAIVDTMNFIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEHLLRTRNTLE
KILAENSGKSVEQIHKDAERDYWMSAQETLEYGFIDEIMENSNLS

Nucleotide


Download         Length: 618 bp        

>NTDB_id=27531 SSA_RS08410 WP_223311179.1 1716308..1716925(-) (clpP) [Streptococcus sanguinis SK36]
ATTTTAAAAAGAGAAAGAGAGAAAACTATGATTCCTGTAGTTATTGAACAAACCAGCCGAGGGGAGCGCTCCTATGATAT
TTACTCCCGGCTATTAAAAGATCGGATTATCATGCTGACTGGTCCAGTAGAGGATAATATGGCTAATTCAATCATTGCCC
AGCTTCTTTTCTTGGATGCACAGGACAATACTAAAGATATTTATCTCTATGTGAATACGCCGGGCGGATCCGTTTCAGCA
GGTCTAGCTATTGTGGACACTATGAACTTCATCAAGTCTGATGTTCAGACCATTGTTATGGGTGTAGCTGCTAGCATGGG
AACAATCATTGCTTCCAGTGGTGCTAAGGGCAAACGCTTCATGCTTCCAAATGCAGAATATCTGATTCACCAGCCAATGG
GCGGAGCTGGAAGTGGTACTCAGCAAACGGATATGGCCATTGTAGCTGAGCACTTGCTTAGAACTCGTAATACCTTGGAA
AAAATCTTGGCCGAAAACTCTGGCAAGTCCGTTGAGCAAATCCATAAGGATGCGGAACGCGATTACTGGATGAGTGCTCA
GGAAACCTTGGAATACGGCTTTATTGACGAAATCATGGAAAATAGCAATCTGAGCTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(20-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

89.796

95.61

0.859
  clpP Streptococcus pneumoniae D39

89.796

95.61

0.859
  clpP Streptococcus pneumoniae R6

89.796

95.61

0.859
  clpP Streptococcus pneumoniae TIGR4

89.796

95.61

0.859
  clpP Streptococcus mutans UA159

88

97.561

0.859
  clpP Streptococcus thermophilus LMG 18311

89.231

95.122

0.849
  clpP Streptococcus pyogenes JRS4

89.231

95.122

0.849
  clpP Streptococcus pyogenes MGAS315

89.231

95.122

0.849
  clpP Streptococcus thermophilus LMD-9

89.231

95.122

0.849
  clpP Lactococcus lactis subsp. cremoris KW2

88.205

95.122

0.839
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.692

95.122

0.834
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

60.104

94.146

0.566
  clpP Bacillus subtilis subsp. subtilis str. 168

56.995

94.146

0.537

Multiple sequence alignment