Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SSA_RS07640 Genome accession   NC_009009
Coordinates   1568698..1569399 (-) Length   233 a.a.
NCBI ID   WP_002894937.1    Uniprot ID   A0A0B7GM19
Organism   Streptococcus sanguinis SK36     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1563698..1574399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS07620 (SSA_1561) rnc 1565275..1565973 (-) 699 WP_002903151.1 ribonuclease III -
  SSA_RS07625 (SSA_1562) - 1566095..1566454 (-) 360 WP_004192874.1 DUF454 family protein -
  SSA_RS07630 (SSA_1563) vicX 1566546..1567346 (-) 801 WP_011837210.1 MBL fold metallo-hydrolase Regulator
  SSA_RS07635 (SSA_1564) micB 1567356..1568705 (-) 1350 WP_002899938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SSA_RS07640 (SSA_1565) micA 1568698..1569399 (-) 702 WP_002894937.1 response regulator YycF Regulator
  SSA_RS07645 (SSA_1566) - 1569739..1570500 (+) 762 WP_011837211.1 amino acid ABC transporter ATP-binding protein -
  SSA_RS07650 (SSA_1567) - 1570515..1571327 (+) 813 WP_011837212.1 transporter substrate-binding domain-containing protein -
  SSA_RS07655 (SSA_1568) - 1571340..1572020 (+) 681 WP_002906090.1 amino acid ABC transporter permease -
  SSA_RS07660 (SSA_1569) - 1572031..1572690 (+) 660 WP_002894927.1 amino acid ABC transporter permease -
  SSA_RS07665 (SSA_1570) - 1572799..1573197 (+) 399 WP_011837213.1 hypothetical protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26735.63 Da        Isoelectric Point: 4.7458

>NTDB_id=27529 SSA_RS07640 WP_002894937.1 1568698..1569399(-) (micA) [Streptococcus sanguinis SK36]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALEMFEAEQPDILILDLMLPEVDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRADLVVENQVEESGPNELTIGELQILPDAFVAKKHGKELELTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=27529 SSA_RS07640 WP_002894937.1 1568698..1569399(-) (micA) [Streptococcus sanguinis SK36]
ATGAAGAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAAGAAGGCTATGA
GGTTTTGACTGCTTTTGATGGTAAGGAAGCCTTGGAAATGTTTGAAGCAGAACAGCCAGACATCTTGATTCTGGACTTGA
TGCTGCCGGAAGTGGACGGACTGGAAGTTGCTCGGACTATTCGCAAGACCAGCAATGTTCCGATTATTGTATTGTCTGCT
AAGGACAGTGAGTTTGACAAGGTTATCGGCCTTGAAATCGGTGCAGATGACTATGTGACCAAGCCTTTCTCAAATCGTGA
GCTGCAGGCGCGTGTCAAGGCACTTCTTCGTCGGGCAGACCTTGTTGTGGAAAACCAAGTAGAAGAAAGTGGCCCGAACG
AGTTGACCATTGGAGAACTGCAGATTTTGCCAGATGCTTTTGTTGCTAAGAAGCATGGCAAGGAGCTGGAGCTGACCCAC
CGTGAGTTTGAACTTCTTCACCATTTGGCGACACATATCGGACAAGTGATGACACGTGAGCACTTGCTGGAAACAGTATG
GGGCTATGACTATTTTGGTGATGTTCGTACAGTGGATGTCACAATCCGCCGCCTGCGTGAAAAGATTGAAGATACGCCAA
GCCGACCTGAGTATATCTTGACTCGCCGCGGAGTTGGCTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7GM19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

80.426

100

0.811
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.231

98.283

0.425
  covR Streptococcus salivarius strain HSISS4

42.174

98.712

0.416
  scnR Streptococcus mutans UA159

36.957

98.712

0.365

Multiple sequence alignment