Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SSA_RS07635 Genome accession   NC_009009
Coordinates   1567356..1568705 (-) Length   449 a.a.
NCBI ID   WP_002899938.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1562356..1573705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS07620 (SSA_1561) rnc 1565275..1565973 (-) 699 WP_002903151.1 ribonuclease III -
  SSA_RS07625 (SSA_1562) - 1566095..1566454 (-) 360 WP_004192874.1 DUF454 family protein -
  SSA_RS07630 (SSA_1563) vicX 1566546..1567346 (-) 801 WP_011837210.1 MBL fold metallo-hydrolase Regulator
  SSA_RS07635 (SSA_1564) micB 1567356..1568705 (-) 1350 WP_002899938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SSA_RS07640 (SSA_1565) micA 1568698..1569399 (-) 702 WP_002894937.1 response regulator YycF Regulator
  SSA_RS07645 (SSA_1566) - 1569739..1570500 (+) 762 WP_011837211.1 amino acid ABC transporter ATP-binding protein -
  SSA_RS07650 (SSA_1567) - 1570515..1571327 (+) 813 WP_011837212.1 transporter substrate-binding domain-containing protein -
  SSA_RS07655 (SSA_1568) - 1571340..1572020 (+) 681 WP_002906090.1 amino acid ABC transporter permease -
  SSA_RS07660 (SSA_1569) - 1572031..1572690 (+) 660 WP_002894927.1 amino acid ABC transporter permease -
  SSA_RS07665 (SSA_1570) - 1572799..1573197 (+) 399 WP_011837213.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50975.86 Da        Isoelectric Point: 4.3896

>NTDB_id=27528 SSA_RS07635 WP_002899938.1 1567356..1568705(-) (micB) [Streptococcus sanguinis SK36]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=27528 SSA_RS07635 WP_002899938.1 1567356..1568705(-) (micB) [Streptococcus sanguinis SK36]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCTATCATTATTATCGGCTTCATTGTAGTTGT
TGCCTTGCTGTTATTGGAAAATCGCCGGGATAATCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GGGACTATTCTGAAGTGCTGGACATGCAGGGCAGTCCGGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACTAACCGTCGGGGGCAGATTATCACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGCGCGACTTGATTACCAATGTTCCTGAG
CTGACGATTGATTCTCAGGATGAAAATGGTGAGTATTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTGGCTGTCTTGCACGACACGACAGAGCAGGACAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCATGAGTTGCGTACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCTTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCGCCGGACTTTGTCAAGGTATCACTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACCTACTTAG
TCTGTCTCGTATTGATAATGAGACCAGTCATCTGGAAGTGGAGCTGACGAATTTCACGGCCTTTATCACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAAACCAAGAAATATGAGATTATCCGTGATTATCCGATAACACCGATTTGG
GTAGAGATTGATACAGATAAGCTGACCCAAGTGATTGATAATATCATGAACAATGCCATCAAGTATTCGCCAGATGGTGG
AACCATTACTGTTTCCATCAAGACAACAGATGAGCAGTTGATTCTCTCAATTGCAGATGAAGGTCTGGGGATTCCCAAGC
AAGACCTGCCTAAGATTTTTGATCGCTTTTATCGAGTGGATAAGGCACGCAGTCGTGCACAGGGTGGAACGGGTCTAGGG
CTGGCTATTGCCAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGTGTTCGGGATGACGACTGGGATAATGAAGACGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.773

0.768
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment