Detailed information NTG0273756

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RL06_RS06470
• Genome accession: NZ_CP026953
• Coordinates: 1173658..1174545 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FDAARGOS_48
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1168658..1179545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL06_RS06435 (RL06_06435)	-	1168677..1168769 (+)	93	WP_010956583.1	hypothetical protein	-
RL06_RS06440 (RL06_06440)	-	1168877..1169374 (-)	498	WP_001065268.1	glutathione peroxidase	-
RL06_RS06445 (RL06_06445)	-	1169384..1169644 (-)	261	WP_001791974.1	hypothetical protein	-
RL06_RS06455 (RL06_06455)	-	1170026..1170139 (-)	114	Protein_1190	hypothetical protein	-
RL06_RS06460 (RL06_06460)	-	1170798..1172798 (-)	2001	WP_000776751.1	ABC transporter permease	-
RL06_RS06465 (RL06_06465)	-	1172795..1173550 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RL06_RS06470 (RL06_06470)	braS	1173658..1174545 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RL06_RS06475 (RL06_06475)	braR	1174556..1175221 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RL06_RS06480 (RL06_06480)	-	1175247..1175447 (-)	201	WP_000604730.1	hypothetical protein	-
RL06_RS06485 (RL06_06485)	-	1175645..1177069 (+)	1425	WP_000953755.1	alkaline phosphatase	-
RL06_RS15245 (RL06_06490)	-	1177129..1177230 (-)	102	WP_000731976.1	SE2200 family small protein	-
RL06_RS06495 (RL06_06495)	-	1177352..1177807 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RL06_RS06500 (RL06_06500)	-	1178052..1178813 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=273756 RL06_RS06470 WP_000143425.1 1173658..1174545(-) (braS) [Staphylococcus aureus strain FDAARGOS_48]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=273756 RL06_RS06470 WP_000143425.1 1173658..1174545(-) (braS) [Staphylococcus aureus strain FDAARGOS_48]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1