Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   DZL14_RS06230 Genome accession   NZ_CP031640
Coordinates   1252434..1252616 (-) Length   60 a.a.
NCBI ID   WP_011054726.1    Uniprot ID   A0A0H2UVL5
Organism   Streptococcus pyogenes strain MGAS7888     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1247434..1257616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DZL14_RS06210 (DZL14_06200) - 1247837..1248553 (-) 717 WP_011284965.1 B3/4 domain-containing protein -
  DZL14_RS06215 (DZL14_06205) - 1248567..1249646 (-) 1080 WP_021341002.1 MmcQ/YjbR family DNA-binding protein -
  DZL14_RS06220 (DZL14_06210) - 1249719..1251452 (-) 1734 WP_011284967.1 sensor histidine kinase -
  DZL14_RS06225 (DZL14_06215) - 1251449..1252189 (-) 741 WP_011054725.1 response regulator -
  DZL14_RS06230 (DZL14_06220) prx 1252434..1252616 (-) 183 WP_011054726.1 hypothetical protein Regulator
  DZL14_RS10185 (DZL14_06225) - 1252681..1252968 (-) 288 WP_011106694.1 hypothetical protein -
  DZL14_RS06240 (DZL14_06230) - 1252962..1253537 (-) 576 WP_011054727.1 hypothetical protein -
  DZL14_RS06245 (DZL14_06235) spek 1254013..1254792 (-) 780 WP_011054728.1 streptococcal pyrogenic exotoxin SpeK -
  DZL14_RS06250 (DZL14_06240) - 1255096..1255962 (-) 867 WP_011054729.1 DUF334 domain-containing protein -
  DZL14_RS06255 (DZL14_06245) - 1255950..1256474 (-) 525 WP_011017840.1 type II toxin-antitoxin system antitoxin SocA domain-containing protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6771.70 Da        Isoelectric Point: 3.9944

>NTDB_id=268664 DZL14_RS06230 WP_011054726.1 1252434..1252616(-) (prx) [Streptococcus pyogenes strain MGAS7888]
MLTYDEFKQAIDNGYIVGDTVAIVRKNGQIFDYVLPGEKVRPSEVVAEEIVEEVVVELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=268664 DZL14_RS06230 WP_011054726.1 1252434..1252616(-) (prx) [Streptococcus pyogenes strain MGAS7888]
ATGCTAACATACGACGAGTTTAAGCAAGCGATTGACAATGGATATATCGTAGGAGACACAGTAGCGATTGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGCGAAAAAGTCAGACCGTCGGAGGTTGTGGCTGAGGAAATAGTGGAAGAGG
TGGTGGTGGAATTAGACAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UVL5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1
  prx Streptococcus pyogenes MGAS8232

80

100

0.8
  prx Streptococcus pyogenes MGAS315

80

100

0.8
  prx Streptococcus pyogenes MGAS315

80

100

0.8
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783
  prx Streptococcus pyogenes MGAS315

73.333

100

0.733
  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6