Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPD_RS02540 Genome accession   NC_008533
Coordinates   481010..482686 (-) Length   558 a.a.
NCBI ID   WP_306423909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae D39     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 476010..487686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPD_RS02510 (SPD_0466) - 476345..476674 (-) 330 WP_000132569.1 hypothetical protein -
  SPD_RS02515 (SPD_0467) - 476950..477288 (+) 339 WP_000682124.1 LytTR family DNA-binding domain-containing protein -
  SPD_RS02520 (SPD_0468) comE/blpR 477293..478030 (+) 738 WP_001219139.1 response regulator transcription factor Regulator
  SPD_RS02525 (SPD_0469) - 478044..479384 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPD_RS02530 (SPD_0470) blpC 479426..479581 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  SPD_RS02535 (SPD_0471) - 479638..480999 (-) 1362 Protein_471 bacteriocin secretion accessory protein -
  SPD_RS02540 (SPD_0472) comA/nlmT 481010..482686 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  SPD_RS12060 comA/nlmT 482580..483167 (-) 588 WP_001856103.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPD_RS02545 - 483457..483690 (+) 234 WP_001093273.1 hypothetical protein -
  SPD_RS02550 (SPD_0473) - 483722..484411 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  SPD_RS02555 (SPD_0474) blpZ 484453..484686 (+) 234 WP_000276498.1 immunity protein BlpZ -
  SPD_RS02565 (SPD_0475) - 484837..485448 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -
  SPD_RS02570 (SPD_0476) ccrZ 485609..486403 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -
  SPD_RS02575 (SPD_0477) trmB 486400..487035 (+) 636 WP_001266083.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  SPD_RS02580 (SPD_0478) rimP 487161..487640 (+) 480 WP_001810863.1 ribosome maturation factor RimP -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62978.29 Da        Isoelectric Point: 7.1280

>NTDB_id=26687 SPD_RS02540 WP_306423909.1 481010..482686(-) (comA/nlmT) [Streptococcus pneumoniae D39]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=26687 SPD_RS02540 WP_306423909.1 481010..482686(-) (comA/nlmT) [Streptococcus pneumoniae D39]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment