Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPD_RS12060 Genome accession   NC_008533
Coordinates   482580..483167 (-) Length   195 a.a.
NCBI ID   WP_001856103.1    Uniprot ID   A7XHI1
Organism   Streptococcus pneumoniae D39     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 477580..488167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPD_RS02525 (SPD_0469) - 478044..479384 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPD_RS02530 (SPD_0470) blpC 479426..479581 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  SPD_RS02535 (SPD_0471) - 479638..480999 (-) 1362 Protein_471 bacteriocin secretion accessory protein -
  SPD_RS02540 (SPD_0472) comA/nlmT 481010..482686 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  SPD_RS12060 comA/nlmT 482580..483167 (-) 588 WP_001856103.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPD_RS02545 - 483457..483690 (+) 234 WP_001093273.1 hypothetical protein -
  SPD_RS02550 (SPD_0473) - 483722..484411 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  SPD_RS02555 (SPD_0474) blpZ 484453..484686 (+) 234 WP_000276498.1 immunity protein BlpZ -
  SPD_RS02565 (SPD_0475) - 484837..485448 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -
  SPD_RS02570 (SPD_0476) ccrZ 485609..486403 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -
  SPD_RS02575 (SPD_0477) trmB 486400..487035 (+) 636 WP_001266083.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  SPD_RS02580 (SPD_0478) rimP 487161..487640 (+) 480 WP_001810863.1 ribosome maturation factor RimP -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22352.81 Da        Isoelectric Point: 9.7004

>NTDB_id=26716 SPD_RS12060 WP_001856103.1 482580..483167(-) (comA/nlmT) [Streptococcus pneumoniae D39]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQAYKTLFDMSDV
PYPFIVHVNKEGKFQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=26716 SPD_RS12060 WP_001856103.1 482580..483167(-) (comA/nlmT) [Streptococcus pneumoniae D39]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCATATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAATTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7XHI1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

58.791

93.333

0.549
  comA Streptococcus mitis NCTC 12261

53.804

94.359

0.508
  comA Streptococcus mitis SK321

53.261

94.359

0.503
  comA Streptococcus pneumoniae Rx1

52.717

94.359

0.497
  comA Streptococcus pneumoniae D39

52.717

94.359

0.497
  comA Streptococcus pneumoniae R6

52.717

94.359

0.497
  comA Streptococcus pneumoniae TIGR4

52.717

94.359

0.497
  comA Streptococcus gordonii str. Challis substr. CH1

51.63

94.359

0.487

Multiple sequence alignment