Detailed information NTG0026560

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LACR_RS06270
• Genome accession: NC_008527
• Coordinates: 1215144..1215992 (-)
• Length: 282 a.a.
• NCBI ID: WP_011676300.1
• Uniprot ID: A0A896TAG0
• Organism: Lactococcus cremoris subsp. cremoris SK11
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1210144..1220992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACR_RS06255 (LACR_1302)	xerS	1210214..1211284 (+)	1071	WP_011676297.1	tyrosine recombinase XerS	-
LACR_RS06260 (LACR_1303)	trmFO	1211334..1212680 (-)	1347	WP_011676298.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
LACR_RS06265 (LACR_1304)	topA	1212752..1214878 (-)	2127	WP_011676299.1	type I DNA topoisomerase	-
LACR_RS06270 (LACR_1305)	dprA	1215144..1215992 (-)	849	WP_011676300.1	DNA-processing protein DprA	Machinery gene
LACR_RS06275 (LACR_1306)	-	1216141..1216521 (-)	381	WP_011676301.1	RidA family protein	-
LACR_RS06280 (LACR_1307)	budA	1216561..1217271 (-)	711	WP_011676302.1	acetolactate decarboxylase	-
LACR_RS06285 (LACR_1308)	ilvA	1217406..1218655 (-)	1250	Protein_1216	threonine ammonia-lyase IlvA	-
LACR_RS06290 (LACR_1309)	ilvC	1218714..1219736 (-)	1023	WP_011676303.1	ketol-acid reductoisomerase	-
LACR_RS06295 (LACR_1310)	ilvN	1219782..1220258 (-)	477	WP_011676304.1	acetolactate synthase small subunit	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31955.09 Da
• Isoelectric Point: 9.8385

>NTDB_id=26560 LACR_RS06270 WP_011676300.1 1215144..1215992(-) (dprA) [Lactococcus cremoris subsp. cremoris SK11]
MITNFDLFRWKKAGMTNLGVNKLLKFFRKYDIKISLRQMGQVAQVKSIPNFIEQYKNQDVKKLRIDYKKFSSFSILDDLY
PERLREIYNPPVLIFYQGNIDLLKNPKLAFVGSRLAGQSGIKAVQKIITELNQSFTIVSGLAKGIDTASHLSAIKTKTPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLVLSEYSLGEKPLKYHFPERNRIIAGLSRGVVVVEEKLRSGSLITCERALEEG
RDIFAIPGNIADGTSDGCNHLIQQGAKLVYQAQDILEEYLYN

Nucleotide

• Length: 849 bp

>NTDB_id=26560 LACR_RS06270 WP_011676300.1 1215144..1215992(-) (dprA) [Lactococcus cremoris subsp. cremoris SK11]
ATGATTACAAATTTTGATTTATTTCGTTGGAAAAAAGCAGGAATGACCAATCTTGGTGTAAATAAGCTCTTAAAATTTTT
CCGCAAATATGATATAAAAATAAGCTTACGACAAATGGGACAAGTGGCTCAAGTCAAATCAATCCCTAACTTTATCGAAC
AATATAAAAATCAGGACGTAAAGAAACTCAGGATAGACTATAAAAAATTTTCCTCCTTTTCCATTCTTGATGACCTTTAT
CCCGAGCGTCTAAGAGAAATCTACAACCCACCCGTTTTAATTTTTTATCAGGGAAATATTGATTTATTAAAAAATCCTAA
ACTTGCCTTTGTTGGAAGCCGCCTAGCAGGTCAATCAGGGATAAAAGCTGTCCAAAAAATTATCACAGAATTGAATCAAT
CCTTTACAATAGTAAGCGGGCTTGCTAAAGGGATTGACACAGCCAGCCATCTGTCAGCAATTAAAACTAAAACACCAACA
ATTGCTGTTATTGGTACAGGATTGGATATTTTCTATCCACTAGAAAATCGTAAAATACAGGAATATCTAGCAAAAAATCA
ATTAGTTTTAAGTGAATATTCATTAGGCGAAAAACCACTTAAATACCACTTTCCAGAGCGCAATCGAATTATTGCTGGTC
TTTCACGGGGAGTTGTTGTCGTGGAAGAAAAATTAAGAAGTGGCAGTTTAATCACCTGTGAAAGGGCACTGGAAGAAGGA
AGAGATATCTTTGCCATCCCTGGAAATATTGCAGATGGAACATCTGATGGCTGTAATCATCTTATTCAACAAGGAGCAAA
ACTTGTCTATCAAGCTCAAGATATTTTAGAAGAATATTTGTACAATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	97.872	100	0.979
dprA	Streptococcus mutans UA159	58.993	98.582	0.582
dprA/cilB/dalA	Streptococcus mitis SK321	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus pneumoniae R6	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae D39	55.357	99.291	0.55
dprA	Bacillus subtilis subsp. subtilis str. 168	39.273	97.518	0.383
dprA	Vibrio campbellii strain DS40M4	35.314	100	0.379
dprA	Legionella pneumophila strain ERS1305867	38.768	97.872	0.379
dprA	Haemophilus influenzae Rd KW20	39.259	95.745	0.376