Detailed information NTG0265286

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: C2H91_RS13610
• Genome accession: NZ_CP026030
• Coordinates: 2749052..2749645 (-)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain PK3_9
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2744052..2754645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H91_RS13595 (C2H91_13615)	mdxK	2744386..2746659 (+)	2274	WP_249851335.1	maltose phosphorylase	-
C2H91_RS13600 (C2H91_13620)	malL	2746652..2748337 (+)	1686	WP_249850834.1	oligo-1,6-glucosidase	-
C2H91_RS13605 (C2H91_13625)	pgmB	2748334..2749008 (+)	675	WP_249850835.1	beta-phosphoglucomutase	-
C2H91_RS13610 (C2H91_13630)	clpP	2749052..2749645 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
C2H91_RS13620 (C2H91_13640)	yvdQ	2750146..2750658 (+)	513	WP_014478056.1	DUF3231 family protein	-
C2H91_RS13625 (C2H91_13645)	psmB	2750694..2751014 (-)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
C2H91_RS13630 (C2H91_13650)	psmA	2751014..2751349 (-)	336	WP_049140398.1	SMR family transporter	-
C2H91_RS13635 (C2H91_13655)	-	2751432..2752016 (-)	585	WP_249850836.1	TetR family transcriptional regulator	-
C2H91_RS13640 (C2H91_13660)	aspP	2752111..2753673 (-)	1563	WP_003228228.1	aspartate/proton symporter AspP	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=265286 C2H91_RS13610 WP_003228214.1 2749052..2749645(-) (clpP) [Bacillus subtilis strain PK3_9]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=265286 C2H91_RS13610 WP_003228214.1 2749052..2749645(-) (clpP) [Bacillus subtilis strain PK3_9]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538