Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C1H71_RS06445 Genome accession   NZ_CP025781
Coordinates   1465265..1466488 (+) Length   407 a.a.
NCBI ID   WP_130105823.1    Uniprot ID   A0A7G3G7D7
Organism   Iodobacter fluviatilis strain PCH194     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1449815..1471479 1465265..1466488 within 0


Gene organization within MGE regions


Location: 1449815..1471479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1H71_RS06365 (C1H71_06430) icd 1450432..1451655 (+) 1224 WP_130105810.1 NADP-dependent isocitrate dehydrogenase -
  C1H71_RS06370 (C1H71_06435) - 1451777..1451980 (-) 204 WP_046351602.1 cold-shock protein -
  C1H71_RS06375 (C1H71_06440) - 1452093..1452296 (-) 204 WP_046351601.1 cold-shock protein -
  C1H71_RS06380 (C1H71_06445) clpS 1452608..1452919 (+) 312 WP_130105811.1 ATP-dependent Clp protease adapter ClpS -
  C1H71_RS06385 (C1H71_06450) clpA 1452916..1455180 (+) 2265 WP_130105812.1 ATP-dependent Clp protease ATP-binding subunit ClpA -
  C1H71_RS06390 (C1H71_06455) - 1455265..1456089 (-) 825 WP_130105813.1 mechanosensitive ion channel family protein -
  C1H71_RS06395 (C1H71_06460) xerD 1456153..1457076 (-) 924 WP_130105814.1 site-specific tyrosine recombinase XerD -
  C1H71_RS21345 (C1H71_06465) - 1457054..1457542 (-) 489 WP_130105815.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  C1H71_RS06405 (C1H71_06470) rplS 1457622..1458005 (-) 384 WP_130105816.1 50S ribosomal protein L19 -
  C1H71_RS06410 (C1H71_06475) trmD 1458047..1458835 (-) 789 WP_374704454.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  C1H71_RS06415 (C1H71_06480) rimM 1458828..1459361 (-) 534 WP_262488407.1 ribosome maturation factor RimM -
  C1H71_RS06420 (C1H71_06485) rpsP 1459370..1459627 (-) 258 WP_130105818.1 30S ribosomal protein S16 -
  C1H71_RS06425 (C1H71_06490) ffh 1459857..1461209 (-) 1353 WP_130105819.1 signal recognition particle protein -
  C1H71_RS06430 (C1H71_06495) - 1461269..1462111 (+) 843 WP_130105820.1 inner membrane protein YpjD -
  C1H71_RS06435 (C1H71_06500) - 1462150..1463412 (+) 1263 WP_130105821.1 HlyC/CorC family transporter -
  C1H71_RS06440 (C1H71_06505) pilB 1463537..1465246 (+) 1710 WP_130105822.1 type IV-A pilus assembly ATPase PilB Machinery gene
  C1H71_RS06445 (C1H71_06510) pilC 1465265..1466488 (+) 1224 WP_130105823.1 type II secretion system F family protein Machinery gene
  C1H71_RS06450 (C1H71_06515) pilD 1466488..1467357 (+) 870 WP_130105824.1 A24 family peptidase Machinery gene
  C1H71_RS06455 (C1H71_06520) coaE 1467372..1467965 (+) 594 WP_130105825.1 dephospho-CoA kinase -
  C1H71_RS06460 (C1H71_06525) zapD 1468044..1468802 (+) 759 WP_130105826.1 cell division protein ZapD -
  C1H71_RS06465 (C1H71_06530) - 1468799..1468990 (+) 192 WP_130105827.1 DNA gyrase inhibitor YacG -
  C1H71_RS06470 (C1H71_06535) - 1469083..1469826 (+) 744 WP_130105828.1 GNAT family N-acetyltransferase -
  C1H71_RS06475 (C1H71_06540) - 1470011..1470685 (+) 675 WP_188053627.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44475.62 Da        Isoelectric Point: 9.8067

>NTDB_id=263739 C1H71_RS06445 WP_130105823.1 1465265..1466488(+) (pilC) [Iodobacter fluviatilis strain PCH194]
MAVASKALKVKEFTFVWEGKDRGGKIVKGEMRASGEHVVKNTLRRQGVNVLKVKKQRMGSSKKITDEDITMFTRQLATML
KSGVPLLTSFDIVAKGHSNPSVTKLLLDIKNDIETGSSLTQAFRKHPNEFDALYCNLIQAGEQAGILDALLARLATYKEK
TLGVKKKIKSALFYPTAVIVAAFVITAVIMIFVIPAFKELFSSFGANLPTPTLVVMAISDVFVTYWWLIFGGIFGGIWGF
LKAWKKSEAIQIVMDRLLLKIPIIGQIMLNATIARWCRTLSTMFAAGVPLVESLDSVGGAAGNYLYKIATKKIQNEVSTG
TSLTLSMQSTNMFPNMVMQMVAIGEESGALDSMLSKVADYYEEEVDNAVEALSSLMEPIIMVVLGTLIGGLVVAMYLPIF
KMGEVVG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=263739 C1H71_RS06445 WP_130105823.1 1465265..1466488(+) (pilC) [Iodobacter fluviatilis strain PCH194]
ATGGCAGTAGCATCTAAAGCCCTAAAAGTAAAAGAATTTACTTTTGTATGGGAAGGTAAAGATCGTGGCGGCAAAATAGT
TAAGGGCGAAATGCGTGCCAGTGGCGAGCACGTCGTAAAAAACACGCTGCGGCGCCAGGGTGTTAATGTTCTAAAAGTAA
AGAAACAACGCATGGGCTCCAGTAAGAAAATTACTGACGAAGATATCACCATGTTTACACGCCAGCTTGCCACCATGCTC
AAGTCAGGGGTTCCTTTACTTACCTCATTTGATATCGTCGCAAAAGGCCATAGCAATCCATCCGTAACCAAGTTGCTTTT
AGATATCAAAAACGATATTGAAACCGGATCGTCCCTTACTCAAGCCTTTAGAAAACACCCTAATGAATTTGATGCGCTGT
ATTGCAACTTAATTCAAGCGGGTGAACAAGCTGGTATTTTGGATGCCCTACTCGCACGGCTTGCTACGTATAAAGAAAAA
ACACTTGGCGTTAAAAAGAAAATTAAATCGGCACTATTTTATCCAACTGCCGTGATTGTTGCTGCATTTGTGATTACGGC
AGTCATTATGATTTTTGTTATTCCCGCATTTAAGGAGCTATTTTCTAGCTTTGGTGCAAACCTGCCAACACCAACGCTGG
TTGTAATGGCAATTTCAGATGTTTTTGTTACCTACTGGTGGCTCATATTTGGCGGTATTTTTGGTGGGATTTGGGGCTTC
TTAAAAGCGTGGAAAAAATCTGAAGCTATTCAAATCGTGATGGATCGCTTACTGCTAAAAATTCCAATCATTGGGCAAAT
TATGCTTAATGCAACCATTGCGCGCTGGTGCCGCACCTTGTCCACCATGTTTGCAGCAGGAGTGCCATTAGTAGAATCAC
TCGACTCGGTGGGCGGTGCGGCGGGTAATTATCTGTATAAAATTGCCACCAAAAAAATTCAAAATGAAGTAAGTACTGGC
ACTAGCCTCACTTTGTCCATGCAAAGCACCAATATGTTTCCCAATATGGTGATGCAAATGGTCGCAATTGGTGAAGAATC
TGGTGCATTAGATTCAATGCTCAGTAAAGTCGCCGATTATTATGAAGAAGAGGTAGATAACGCCGTTGAAGCGCTTTCCA
GCTTAATGGAGCCCATCATTATGGTGGTCTTAGGTACGCTGATTGGTGGTCTAGTGGTTGCTATGTACTTACCAATTTTC
AAAATGGGCGAGGTTGTCGGTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G3G7D7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

53.266

97.789

0.521
  pilC Pseudomonas stutzeri DSM 10701

51.351

100

0.514
  pilG Neisseria gonorrhoeae MS11

51.889

97.543

0.506
  pilC Acinetobacter baumannii D1279779

51.005

97.789

0.499
  pilG Neisseria meningitidis 44/76-A

51.005

97.789

0.499
  pilC Acinetobacter baylyi ADP1

50.126

97.543

0.489
  pilC Vibrio cholerae strain A1552

39.706

100

0.398
  pilC Vibrio campbellii strain DS40M4

37.093

98.034

0.364

Multiple sequence alignment