Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   C0J00_RS07285 Genome accession   NZ_CP025536
Coordinates   1440932..1441639 (-) Length   235 a.a.
NCBI ID   WP_104968255.1    Uniprot ID   A0A2L0D523
Organism   Streptococcus pluranimalium strain TH11417     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1435932..1446639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS07270 (C0J00_07275) rnc 1437847..1438548 (-) 702 WP_104968252.1 ribonuclease III -
  C0J00_RS07275 (C0J00_07280) vicX 1438782..1439591 (-) 810 WP_104968253.1 MBL fold metallo-hydrolase Regulator
  C0J00_RS07280 (C0J00_07285) vicK 1439593..1440939 (-) 1347 WP_104968254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  C0J00_RS07285 (C0J00_07290) vicR 1440932..1441639 (-) 708 WP_104968255.1 response regulator YycF Regulator
  C0J00_RS07290 (C0J00_07295) - 1441878..1442663 (+) 786 WP_104968256.1 amino acid ABC transporter ATP-binding protein -
  C0J00_RS07295 (C0J00_07300) - 1442674..1443501 (+) 828 WP_104968257.1 transporter substrate-binding domain-containing protein -
  C0J00_RS07300 (C0J00_07305) - 1443520..1444215 (+) 696 WP_104968258.1 amino acid ABC transporter permease -
  C0J00_RS07305 (C0J00_07310) - 1444224..1444874 (+) 651 WP_104968259.1 amino acid ABC transporter permease -
  C0J00_RS07310 (C0J00_07315) - 1444964..1445563 (-) 600 WP_104968260.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26945.82 Da        Isoelectric Point: 4.7489

>NTDB_id=262360 C0J00_RS07285 WP_104968255.1 1440932..1441639(-) (vicR) [Streptococcus pluranimalium strain TH11417]
MKTILVVDDERPISDIIKFNLSKEGYTIETAFDGHDAVEKFEDIKPDLVILDLMLPGMDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAQLRRVETIETVAEESLQSSPTEIEIGNLQILPEAFIAKKNGEEVEL
THREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIETTPSRPEYILTRRGVGYFMKAHD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=262360 C0J00_RS07285 WP_104968255.1 1440932..1441639(-) (vicR) [Streptococcus pluranimalium strain TH11417]
ATGAAAACAATTCTCGTTGTAGATGATGAAAGACCCATCTCAGACATTATAAAATTTAATCTGAGTAAGGAAGGCTATAC
TATTGAAACAGCCTTTGATGGTCATGACGCGGTTGAAAAATTTGAAGATATTAAGCCTGACTTGGTTATTTTGGACTTGA
TGCTACCAGGTATGGATGGTCTTGAGGTAGCTAAAGAGATTCGTAAAACAAGTCACACGCCAATTATTATGTTATCGGCT
AAGGATTCTGAGTTCGATAAGGTGATTGGCTTGGAAATCGGTGCAGATGATTATGTCACAAAACCCTTCTCTAATCGAGA
GTTATTGGCGCGTGTGAAAGCTCAACTACGTCGTGTTGAGACCATTGAAACTGTGGCAGAAGAATCTCTTCAATCCTCTC
CGACAGAAATCGAGATTGGGAACCTTCAAATCTTACCAGAGGCGTTTATTGCTAAAAAGAACGGAGAGGAAGTCGAGCTG
ACGCATCGTGAGTTTGAATTGCTCTATCATTTGGCGCAACATATTGGTCAAGTGATGACACGCGAGCATCTCCTTGAAAC
GGTTTGGGGATATGACTATTTTGGTGATGTTCGGACAGTTGATGTGACTATTCGTCGCCTCCGTGAAAAAATCGAGACAA
CTCCAAGTCGTCCGGAATACATTCTCACTCGTCGTGGAGTGGGATACTTTATGAAAGCTCATGACTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D523

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

79.574

100

0.796
  micA Streptococcus pneumoniae Cp1015

73.932

99.574

0.736
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  covR Streptococcus salivarius strain HSISS4

41.126

98.298

0.404
  scnR Streptococcus mutans UA159

36.864

100

0.37

Multiple sequence alignment