Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   C0J00_RS07280 Genome accession   NZ_CP025536
Coordinates   1439593..1440939 (-) Length   448 a.a.
NCBI ID   WP_104968254.1    Uniprot ID   A0A2L0D530
Organism   Streptococcus pluranimalium strain TH11417     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1434593..1445939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS07270 (C0J00_07275) rnc 1437847..1438548 (-) 702 WP_104968252.1 ribonuclease III -
  C0J00_RS07275 (C0J00_07280) vicX 1438782..1439591 (-) 810 WP_104968253.1 MBL fold metallo-hydrolase Regulator
  C0J00_RS07280 (C0J00_07285) vicK 1439593..1440939 (-) 1347 WP_104968254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  C0J00_RS07285 (C0J00_07290) vicR 1440932..1441639 (-) 708 WP_104968255.1 response regulator YycF Regulator
  C0J00_RS07290 (C0J00_07295) - 1441878..1442663 (+) 786 WP_104968256.1 amino acid ABC transporter ATP-binding protein -
  C0J00_RS07295 (C0J00_07300) - 1442674..1443501 (+) 828 WP_104968257.1 transporter substrate-binding domain-containing protein -
  C0J00_RS07300 (C0J00_07305) - 1443520..1444215 (+) 696 WP_104968258.1 amino acid ABC transporter permease -
  C0J00_RS07305 (C0J00_07310) - 1444224..1444874 (+) 651 WP_104968259.1 amino acid ABC transporter permease -
  C0J00_RS07310 (C0J00_07315) - 1444964..1445563 (-) 600 WP_104968260.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 51137.14 Da        Isoelectric Point: 4.7338

>NTDB_id=262359 C0J00_RS07280 WP_104968254.1 1439593..1440939(-) (vicK) [Streptococcus pluranimalium strain TH11417]
MTDQFLFSFRDVIIAGLMSILVLIYVFLIIRDTLNSRRVQQLTEQVQALISGEYVVNQVTRGSAEVKDLAEHLNDLSEVF
RLTHENLGQEKNRLSSILSYMSDGVLATDRRGNIIMINDMARQQLNLSEEGDLAINIMTLLEDTSYTYHDLITKTPEVTL
HRVDEFGEFTVLRVNFALIKRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEAV
APGFIRVSLDETNRMMRMITDLLSLSRIDNNNSELEVELTNFTAFITYILNRFDRIKLQETHAGKSYDIKRNYDLTPVWI
EIDNDKMTQVFDNILNNAIKYSPDGGEIKVSMRTTDTQLIVSVSDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGL
AITKEIVKQHNGFIWAKSDYGKGSTFTIVLPYEKNILEVDEEWEVTED

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=262359 C0J00_RS07280 WP_104968254.1 1439593..1440939(-) (vicK) [Streptococcus pluranimalium strain TH11417]
ATGACTGATCAATTTCTTTTTTCATTTCGAGATGTTATTATTGCAGGGCTAATGTCAATTTTAGTCCTGATTTATGTTTT
TTTAATTATTCGAGATACTTTAAATAGTCGACGTGTGCAACAATTGACGGAGCAAGTTCAAGCCTTGATTTCAGGTGAGT
ATGTGGTCAATCAGGTAACACGAGGAAGTGCTGAAGTTAAGGACTTAGCTGAACATTTGAACGATCTATCTGAGGTTTTT
CGTCTAACACATGAAAATTTAGGACAAGAAAAAAATCGTCTTTCAAGTATTTTATCCTATATGAGCGATGGGGTTTTAGC
AACAGACCGTCGTGGTAATATCATTATGATTAATGATATGGCAAGGCAACAGTTGAACTTATCAGAAGAAGGTGACCTTG
CCATCAATATTATGACTTTGTTGGAAGATACCTCGTATACTTATCATGATTTAATAACCAAAACACCCGAAGTAACGCTT
CACCGTGTCGATGAGTTTGGTGAATTTACGGTGCTGAGGGTCAATTTTGCTCTTATCAAGAGAGAGAGTGGTTTTATATC
TGGTTTGGTAGCCGTTTTACACGATACAACAGAACAAGAAAAAGAGGAACGTGAACGTCGTCTCTTTGTTTCCAATGTTA
GTCATGAATTACGGACTCCTCTAACATCGGTAAAGTCGTATCTTGAAGCCTTGGATGAAGGGGCCCTTAAGGAAGCTGTT
GCCCCTGGGTTTATCCGTGTTTCTTTAGATGAAACAAACAGGATGATGCGGATGATTACAGACTTGCTATCCCTATCACG
TATTGATAATAATAATAGTGAATTAGAAGTTGAACTGACGAACTTTACAGCTTTTATCACCTATATCCTAAATCGTTTTG
ACCGCATCAAGTTACAGGAAACACATGCAGGAAAATCTTATGATATTAAGCGCAACTACGATCTGACTCCTGTTTGGATT
GAGATTGATAATGATAAGATGACCCAAGTTTTCGATAATATTTTAAACAATGCTATCAAGTATTCACCAGATGGTGGGGA
GATTAAGGTGAGCATGCGAACGACTGATACTCAATTAATTGTATCGGTATCTGACCAAGGATTGGGAATTCCTAAAAAAG
ACTTGCCTTTAATTTTTGACCGTTTCTACCGTGTTGATAAGGCAAGAAGCCGTGCCCAAGGAGGCACTGGACTCGGTCTA
GCAATTACCAAAGAAATTGTTAAACAACACAATGGCTTTATTTGGGCTAAAAGTGATTACGGTAAGGGATCAACGTTTAC
CATCGTTTTACCGTATGAAAAGAATATTTTAGAAGTAGACGAAGAATGGGAGGTAACTGAAGACTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(206-270)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(323-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D530

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

71.29

91.741

0.654
  micB Streptococcus pneumoniae Cp1015

64.896

96.652

0.627

Multiple sequence alignment