Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CRH08_RS06530 Genome accession   NZ_CP025419
Coordinates   1268631..1269302 (-) Length   223 a.a.
NCBI ID   WP_009909965.1    Uniprot ID   A0A075SH40
Organism   Streptococcus suis strain SH0104     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1263631..1274302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRH08_RS06505 coaA 1264217..1265137 (+) 921 WP_002935283.1 type I pantothenate kinase -
  CRH08_RS06510 rpsT 1265196..1265444 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  CRH08_RS06515 - 1265706..1266935 (-) 1230 WP_002935288.1 transglutaminase domain-containing protein -
  CRH08_RS06525 ciaH 1267259..1268638 (-) 1380 WP_002935290.1 HAMP domain-containing sensor histidine kinase Regulator
  CRH08_RS06530 ciaR 1268631..1269302 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  CRH08_RS06535 - 1269496..1269786 (-) 291 WP_013730395.1 hypothetical protein -
  CRH08_RS06540 - 1270218..1270595 (-) 378 WP_024394270.1 PBECR2 nuclease fold domain-containing protein -
  CRH08_RS06545 - 1270660..1271397 (-) 738 WP_014636660.1 PlySs2 family phage lysin -
  CRH08_RS06550 - 1271381..1271731 (-) 351 WP_002937841.1 phage holin -
  CRH08_RS06555 - 1271734..1272033 (-) 300 WP_014636661.1 hypothetical protein -
  CRH08_RS06560 - 1272037..1272381 (-) 345 WP_002937844.1 hypothetical protein -
  CRH08_RS06565 - 1272384..1272602 (-) 219 WP_002937846.1 hypothetical protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25290.00 Da        Isoelectric Point: 4.2183

>NTDB_id=261116 CRH08_RS06530 WP_009909965.1 1268631..1269302(-) (ciaR) [Streptococcus suis strain SH0104]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=261116 CRH08_RS06530 WP_009909965.1 1268631..1269302(-) (ciaR) [Streptococcus suis strain SH0104]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SH40

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

100

0.901
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.47

100

0.372
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.363

Multiple sequence alignment