Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   CRH08_RS06525 Genome accession   NZ_CP025419
Coordinates   1267259..1268638 (-) Length   459 a.a.
NCBI ID   WP_002935290.1    Uniprot ID   A0A0Z8I1B6
Organism   Streptococcus suis strain SH0104     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1262259..1273638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRH08_RS06500 - 1263518..1264108 (-) 591 WP_009909951.1 class I SAM-dependent methyltransferase -
  CRH08_RS06505 coaA 1264217..1265137 (+) 921 WP_002935283.1 type I pantothenate kinase -
  CRH08_RS06510 rpsT 1265196..1265444 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  CRH08_RS06515 - 1265706..1266935 (-) 1230 WP_002935288.1 transglutaminase domain-containing protein -
  CRH08_RS06525 ciaH 1267259..1268638 (-) 1380 WP_002935290.1 HAMP domain-containing sensor histidine kinase Regulator
  CRH08_RS06530 ciaR 1268631..1269302 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  CRH08_RS06535 - 1269496..1269786 (-) 291 WP_013730395.1 hypothetical protein -
  CRH08_RS06540 - 1270218..1270595 (-) 378 WP_024394270.1 PBECR2 nuclease fold domain-containing protein -
  CRH08_RS06545 - 1270660..1271397 (-) 738 WP_014636660.1 PlySs2 family phage lysin -
  CRH08_RS06550 - 1271381..1271731 (-) 351 WP_002937841.1 phage holin -
  CRH08_RS06555 - 1271734..1272033 (-) 300 WP_014636661.1 hypothetical protein -
  CRH08_RS06560 - 1272037..1272381 (-) 345 WP_002937844.1 hypothetical protein -
  CRH08_RS06565 - 1272384..1272602 (-) 219 WP_002937846.1 hypothetical protein -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51921.60 Da        Isoelectric Point: 6.8879

>NTDB_id=261115 CRH08_RS06525 WP_002935290.1 1267259..1268638(-) (ciaH) [Streptococcus suis strain SH0104]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSTPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=261115 CRH08_RS06525 WP_002935290.1 1267259..1268638(-) (ciaH) [Streptococcus suis strain SH0104]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCACGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGGTTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGGTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8I1B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

48.791

99.129

0.484

Multiple sequence alignment