Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   CR921_RS05525 Genome accession   NZ_CP025399
Coordinates   1037072..1037779 (-) Length   235 a.a.
NCBI ID   WP_101415635.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain GABA     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1032072..1042779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR921_RS05500 yidA 1032423..1033232 (+) 810 WP_011226081.1 sugar-phosphatase -
  CR921_RS05505 - 1033234..1034448 (+) 1215 WP_002953123.1 aminoacyltransferase -
  CR921_RS05510 - 1034500..1034861 (-) 362 Protein_1011 YbaN family protein -
  CR921_RS05515 vicX 1034921..1035733 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  CR921_RS05520 vicK 1035739..1037079 (-) 1341 WP_101415634.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CR921_RS05525 vicR 1037072..1037779 (-) 708 WP_101415635.1 response regulator YycF Regulator
  CR921_RS05530 - 1038304..1039071 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  CR921_RS05535 - 1039083..1039916 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  CR921_RS05540 - 1039934..1040632 (+) 699 WP_011681209.1 amino acid ABC transporter permease -
  CR921_RS05545 - 1040644..1041294 (+) 651 WP_011226088.1 amino acid ABC transporter permease -
  CR921_RS05550 endA 1041366..1042247 (-) 882 WP_011681210.1 DNA/RNA non-specific endonuclease Machinery gene
  CR921_RS05555 - 1042309..1042497 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27032.90 Da        Isoelectric Point: 5.0130

>NTDB_id=260934 CR921_RS05525 WP_101415635.1 1037072..1037779(-) (vicR) [Streptococcus thermophilus strain GABA]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARSKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=260934 CR921_RS05525 WP_101415635.1 1037072..1037779(-) (vicR) [Streptococcus thermophilus strain GABA]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTAGTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCCAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.32

98.298

0.455
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  scnR Streptococcus mutans UA159

38.136

100

0.383

Multiple sequence alignment